Benefit of anti-TNFα treatment for nephrotic syndrome in a patient with juvenile inflammatory bowel disease associated spondyloarthropathy complicated with amyloidosis and glomerulonephritis

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Figure 1 .

Renal biopsy specimen (A) at baseline and (B) after seven months of treatment. After seven months no decrease in the amount of amyloid is seen despite continuous infliximab treatment. AA stain, x20.

Figure 2 .

Amyloid depositions in glomeruli partly covered by newly formed glomerular basement membrane (x11 500). Inset: amyloid fibrils (x72 500). Arrowhead indicates newly formed basement membrane. E, endothelium; P, podocytes; A, amyloid fibrils.