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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 2004 Feb;63(2):130. doi: 10.1136/ard.2003.013912

Case Number 29: Ochronosis: synovial histopathological characteristics

E Kruithof 1, D Baeten 1, E Veys 1, F De Keyser 1, S Suykens 1, L De Wilde 1, R Verdonk 1
PMCID: PMC1754883  PMID: 14722199

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Figure 1 .

Figure 1

(A) Darkening of the urine by standing; (B) x ray picture of the right shoulder demonstrating a destroyed joint with sclerosis, osteophytosis; (C) slate-blue discolouration of the antihelix of the ear; (D) yellow-brown shards, scattered over the synovium; (E, F) shard evoking a foreign body reaction with multinucleated giant cells and surrounded by pigment loaded macrophages.


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