Effect of etanercept on matrix metalloproteinases and angiogenic vascular endothelial growth factor: a time kinetic study

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Figure 1.

 Box plot showing the percentage change at different times in patients treated with etanercept as compared with the baseline value in each patient (A) MMP-1; (B) TIMP-1; (C) VEGF; (D) 28 tender joint count; (E) 28 swollen joint count. o depicts outliers and * depicts extreme values. †p<0.05, ‡p<0.005. For values with †p_corr was not significant after Bonferroni's correction.