Altered influenza virus haemagglutinin peptides inhibit T cell responses to type II collagen in rheumatoid arthritis

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Figure 1.

 Inhibitory effects of altered HA308–317 peptides on T cell responses to CII263–272. PBMC from patients with RA were cultured for 5 days in the presence of 10 µg/ml CII263–272 and different concentrations of altered HA308–317 peptides (0, 2, 10, and 50 µg/ml, respectively). Results showed that altered HA308–317 peptides suppressed T cell responses to CII263–272 in a range from 2 µg/ml to 50 µg/ml (*p<0.05,**p<0.01).