Full Text
The Full Text of this article is available as a PDF (57.9 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Abdel-Nasser A. M., Rasker J. J., Valkenburg H. A. Epidemiological and clinical aspects relating to the variability of rheumatoid arthritis. Semin Arthritis Rheum. 1997 Oct;27(2):123–140. doi: 10.1016/s0049-0172(97)80012-1. [DOI] [PubMed] [Google Scholar]
- Ashwell J. D., Lu F. W., Vacchio M. S. Glucocorticoids in T cell development and function*. Annu Rev Immunol. 2000;18:309–345. doi: 10.1146/annurev.immunol.18.1.309. [DOI] [PubMed] [Google Scholar]
- Cantorna M. T. Vitamin D and autoimmunity: is vitamin D status an environmental factor affecting autoimmune disease prevalence? Proc Soc Exp Biol Med. 2000 Mar;223(3):230–233. doi: 10.1046/j.1525-1373.2000.22333.x. [DOI] [PubMed] [Google Scholar]
- Carrillo-Vico Antonio, Calvo Juan R., Abreu Pedro, Lardone Patricia J., García-Mauriño Sofía, Reiter Russel J., Guerrero Juan M. Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance. FASEB J. 2004 Jan 8;18(3):537–539. doi: 10.1096/fj.03-0694fje. [DOI] [PubMed] [Google Scholar]
- Carrillo-Vico Antonio, Lardone Patricia J., Fernández-Santos José M., Martín-Lacave Inés, Calvo Juan R., Karasek Michal, Guerrero Juan M. Human lymphocyte-synthesized melatonin is involved in the regulation of the interleukin-2/interleukin-2 receptor system. J Clin Endocrinol Metab. 2004 Nov 23;90(2):992–1000. doi: 10.1210/jc.2004-1429. [DOI] [PubMed] [Google Scholar]
- Corrigan C. J., Brown P. H., Barnes N. C., Tsai J. J., Frew A. J., Kay A. B. Glucocorticoid resistance in chronic asthma. Peripheral blood T lymphocyte activation and comparison of the T lymphocyte inhibitory effects of glucocorticoids and cyclosporin A. Am Rev Respir Dis. 1991 Nov;144(5):1026–1032. doi: 10.1164/ajrccm/144.5.page. [DOI] [PubMed] [Google Scholar]
- Cutolo M., Maestroni G. J. M., Otsa K., Aakre O., Villaggio B., Capellino S., Montagna P., Fazzuoli L., Veldi T., Peets T. Circadian melatonin and cortisol levels in rheumatoid arthritis patients in winter time: a north and south Europe comparison. Ann Rheum Dis. 2005 Feb;64(2):212–216. doi: 10.1136/ard.2004.023416. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cutolo M. Solar light effects on onset/relapses and circannual/circadian symptomatology in rheumatoid arthritis. Clin Exp Rheumatol. 2003 Mar-Apr;21(2):148–150. [PubMed] [Google Scholar]
- Cutolo M., Villaggio B., Candido F., Valenti S., Giusti M., Felli L., Sulli A., Accardo S. Melatonin influences interleukin-12 and nitric oxide production by primary cultures of rheumatoid synovial macrophages and THP-1 cells. Ann N Y Acad Sci. 1999 Jun 22;876:246–254. doi: 10.1111/j.1749-6632.1999.tb07645.x. [DOI] [PubMed] [Google Scholar]
- Cutolo Maurizio, Masi Alfonse T. Circadian rhythms and arthritis. Rheum Dis Clin North Am. 2005 Feb;31(1):115-29, ix-x. doi: 10.1016/j.rdc.2004.09.005. [DOI] [PubMed] [Google Scholar]
- Fiorina P., Lattuada G., Silvestrini C., Ponari O., Dall'Aglio P. Disruption of nocturnal melatonin rhythm and immunological involvement in ischaemic stroke patients. Scand J Immunol. 1999 Aug;50(2):228–231. doi: 10.1046/j.1365-3083.1999.00579.x. [DOI] [PubMed] [Google Scholar]
- Garcia-Mauriño S., Gonzalez-Haba M. G., Calvo J. R., Rafii-El-Idrissi M., Sanchez-Margalet V., Goberna R., Guerrero J. M. Melatonin enhances IL-2, IL-6, and IFN-gamma production by human circulating CD4+ cells: a possible nuclear receptor-mediated mechanism involving T helper type 1 lymphocytes and monocytes. J Immunol. 1997 Jul 15;159(2):574–581. [PubMed] [Google Scholar]
- García-Mauriño S., Pozo D., Carrillo-Vico A., Calvo J. R., Guerrero J. M. Melatonin activates Th1 lymphocytes by increasing IL-12 production. Life Sci. 1999;65(20):2143–2150. doi: 10.1016/s0024-3205(99)00479-8. [DOI] [PubMed] [Google Scholar]
- García-Mauriño S., Pozo D., Carrillo-Vico A., Calvo J. R., Guerrero J. M. Melatonin activates Th1 lymphocytes by increasing IL-12 production. Life Sci. 1999;65(20):2143–2150. doi: 10.1016/s0024-3205(99)00479-8. [DOI] [PubMed] [Google Scholar]
- Kino Tomoshige, Chrousos George P. Tissue-specific glucocorticoid resistance-hypersensitivity syndromes: multifactorial states of clinical importance. J Allergy Clin Immunol. 2002 Apr;109(4):609–613. doi: 10.1067/mai.2002.123708. [DOI] [PubMed] [Google Scholar]
- Kliger C. A., Gehad A. E., Hulet R. M., Roush W. B., Lillehoj H. S., Mashaly M. M. Effects of photoperiod and melatonin on lymphocyte activities in male broiler chickens. Poult Sci. 2000 Jan;79(1):18–25. doi: 10.1093/ps/79.1.18. [DOI] [PubMed] [Google Scholar]
- Leung D. Y., de Castro M., Szefler S. J., Chrousos G. P. Mechanisms of glucocorticoid-resistant asthma. Ann N Y Acad Sci. 1998 May 1;840:735–746. doi: 10.1111/j.1749-6632.1998.tb09612.x. [DOI] [PubMed] [Google Scholar]
- Lissoni P. Modulation of anticancer cytokines IL-2 and IL-12 by melatonin and the other pineal indoles 5-methoxytryptamine and 5-methoxytryptophol in the treatment of human neoplasms. Ann N Y Acad Sci. 2000;917:560–567. doi: 10.1111/j.1749-6632.2000.tb05421.x. [DOI] [PubMed] [Google Scholar]
- Maestroni G. J. M., Sulli A., Pizzorni C., Villaggio B., Cutolo M. Melatonin in rheumatoid arthritis: a disease-promoting and modulating hormone? Clin Exp Rheumatol. 2002 Nov-Dec;20(6):872–873. [PubMed] [Google Scholar]
- Maestroni G. J., Conti A., Lissoni P. Colony-stimulating activity and hematopoietic rescue from cancer chemotherapy compounds are induced by melatonin via endogenous interleukin 4. Cancer Res. 1994 Sep 1;54(17):4740–4743. [PubMed] [Google Scholar]
- Maestroni G. J., Conti A., Pierpaoli W. Role of the pineal gland in immunity. Circadian synthesis and release of melatonin modulates the antibody response and antagonizes the immunosuppressive effect of corticosterone. J Neuroimmunol. 1986 Nov;13(1):19–30. doi: 10.1016/0165-5728(86)90047-0. [DOI] [PubMed] [Google Scholar]
- Maestroni G. J., Conti A., Pierpaoli W. Role of the pineal gland in immunity. III. Melatonin antagonizes the immunosuppressive effect of acute stress via an opiatergic mechanism. Immunology. 1988 Mar;63(3):465–469. [PMC free article] [PubMed] [Google Scholar]
- Maestroni G. J., Conti A. The pineal neurohormone melatonin stimulates activated CD4+, Thy-1+ cells to release opioid agonist(s) with immunoenhancing and anti-stress properties. J Neuroimmunol. 1990 Jul;28(2):167–176. doi: 10.1016/0165-5728(90)90031-h. [DOI] [PubMed] [Google Scholar]
- Maestroni G. J., Covacci V., Conti A. Hematopoietic rescue via T-cell-dependent, endogenous granulocyte-macrophage colony-stimulating factor induced by the pineal neurohormone melatonin in tumor-bearing mice. Cancer Res. 1994 May 1;54(9):2429–2432. [PubMed] [Google Scholar]
- Maestroni G. J. The immunotherapeutic potential of melatonin. Expert Opin Investig Drugs. 2001 Mar;10(3):467–476. doi: 10.1517/13543784.10.3.467. [DOI] [PubMed] [Google Scholar]
- Maestroni G. J. Therapeutic potential of melatonin in immunodeficiency states, viral diseases, and cancer. Adv Exp Med Biol. 1999;467:217–226. doi: 10.1007/978-1-4615-4709-9_28. [DOI] [PubMed] [Google Scholar]
- Maestroni Georges J. M., Sulli Alberto, Pizzorni Carmen, Villaggio Barbara, Cutolo Maurizio. Melatonin in rheumatoid arthritis: synovial macrophages show melatonin receptors. Ann N Y Acad Sci. 2002 Jun;966:271–275. doi: 10.1111/j.1749-6632.2002.tb04226.x. [DOI] [PubMed] [Google Scholar]
- Malek Thomas R., Bayer Allison L. Tolerance, not immunity, crucially depends on IL-2. Nat Rev Immunol. 2004 Sep;4(9):665–674. doi: 10.1038/nri1435. [DOI] [PubMed] [Google Scholar]
- Moore C. B., Siopes T. D. Effects of lighting conditions and melatonin supplementation on the cellular and humoral immune responses in Japanese quail Coturnix coturnix japonica. Gen Comp Endocrinol. 2000 Jul;119(1):95–104. doi: 10.1006/gcen.2000.7496. [DOI] [PubMed] [Google Scholar]
- Morrey K. M., McLachlan J. A., Serkin C. D., Bakouche O. Activation of human monocytes by the pineal hormone melatonin. J Immunol. 1994 Sep 15;153(6):2671–2680. [PubMed] [Google Scholar]
- Nelson Brad H. IL-2, regulatory T cells, and tolerance. J Immunol. 2004 Apr 1;172(7):3983–3988. doi: 10.4049/jimmunol.172.7.3983. [DOI] [PubMed] [Google Scholar]
- Nelson R. J., Demas G. E. Role of melatonin in mediating seasonal energetic and immunologic adaptations. Brain Res Bull. 1997;44(4):423–430. doi: 10.1016/s0361-9230(97)00222-0. [DOI] [PubMed] [Google Scholar]
- Nunnari G., Nigro L., Palermo F., Leto D., Pomerantz R. J., Cacopardo B. Reduction of serum melatonin levels in HIV-1-infected individuals' parallel disease progression: correlation with serum interleukin-12 levels. Infection. 2003 Dec;31(6):379–382. doi: 10.1007/s15010-003-4038-9. [DOI] [PubMed] [Google Scholar]
- Petrovsky N., Harrison L. C. The chronobiology of human cytokine production. Int Rev Immunol. 1998;16(5-6):635–649. doi: 10.3109/08830189809043012. [DOI] [PubMed] [Google Scholar]
- Rafii-El-Idrissi M., Calvo J. R., Harmouch A., García-Mauriño S., Guerrero J. M. Specific binding of melatonin by purified cell nuclei from spleen and thymus of the rat. J Neuroimmunol. 1998 Jun 15;86(2):190–197. doi: 10.1016/s0165-5728(98)00048-4. [DOI] [PubMed] [Google Scholar]
- Rozin A., Balbir-Gurman A., Schapira D. Seasonal distribution of relapse onset in rheumatoid arthritis and spondyloarthropathy: the possible effect of the solar factor. Clin Exp Rheumatol. 2003 Mar-Apr;21(2):161–169. [PubMed] [Google Scholar]
- Sainz R. M., Mayo J. C., Reiter R. J., Antolin I., Esteban M. M., Rodriguez C. Melatonin regulates glucocorticoid receptor: an answer to its antiapoptotic action in thymus. FASEB J. 1999 Sep;13(12):1547–1556. doi: 10.1096/fasebj.13.12.1547. [DOI] [PubMed] [Google Scholar]
- Schulze-Koops H., Lipsky P. E., Kavanaugh A. F., Davis L. S. Elevated Th1- or Th0-like cytokine mRNA in peripheral circulation of patients with rheumatoid arthritis. Modulation by treatment with anti-ICAM-1 correlates with clinical benefit. J Immunol. 1995 Nov 15;155(10):5029–5037. [PubMed] [Google Scholar]
- Sher E. R., Leung D. Y., Surs W., Kam J. C., Zieg G., Kamada A. K., Szefler S. J. Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy. J Clin Invest. 1994 Jan;93(1):33–39. doi: 10.1172/JCI116963. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Spector T. D. Rheumatoid arthritis. Rheum Dis Clin North Am. 1990 Aug;16(3):513–537. [PubMed] [Google Scholar]
- Straub R. H., Cutolo M. Involvement of the hypothalamic--pituitary--adrenal/gonadal axis and the peripheral nervous system in rheumatoid arthritis: viewpoint based on a systemic pathogenetic role. Arthritis Rheum. 2001 Mar;44(3):493–507. doi: 10.1002/1529-0131(200103)44:3<493::AID-ANR95>3.0.CO;2-U. [DOI] [PubMed] [Google Scholar]
- Sulli A., Maestroni G. J. M., Villaggio B., Hertens E., Craviotto C., Pizzorni C., Briata M., Seriolo B., Cutolo M. Melatonin serum levels in rheumatoid arthritis. Ann N Y Acad Sci. 2002 Jun;966:276–283. doi: 10.1111/j.1749-6632.2002.tb04227.x. [DOI] [PubMed] [Google Scholar]
- Walker K. B., Potter J. M., House A. K. Interleukin 2 synthesis in the presence of steroids: a model of steroid resistance. Clin Exp Immunol. 1987 Apr;68(1):162–167. [PMC free article] [PubMed] [Google Scholar]
- Webster Jeanette I., Tonelli Leonardo, Sternberg Esther M. Neuroendocrine regulation of immunity. Annu Rev Immunol. 2001 Oct 4;20:125–163. doi: 10.1146/annurev.immunol.20.082401.104914. [DOI] [PubMed] [Google Scholar]
- Wichmann M. W., Zellweger R., DeMaso, Ayala A., Chaudry I. H. Melatonin administration attenuates depressed immune functions trauma-hemorrhage. J Surg Res. 1996 Jun;63(1):256–262. doi: 10.1006/jsre.1996.0257. [DOI] [PubMed] [Google Scholar]
- Yellon S. M., Teasley L. A., Fagoaga O. R., Nguyen H. C., Truong H. N., Nehlsen-Cannarella L. Role of photoperiod and the pineal gland in T cell-dependent humoral immune reactivity in the Siberian hamster. J Pineal Res. 1999 Nov;27(4):243–248. doi: 10.1111/j.1600-079x.1999.tb00622.x. [DOI] [PubMed] [Google Scholar]