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. 1997 Sep;65(9):3976–3980. doi: 10.1128/iai.65.9.3976-3980.1997

Listeriolysin and IrpA are major protein targets of the human humoral response against Listeria monocytogenes.

R Grenningloh 1, A Darji 1, J Wehland 1, T Chakraborty 1, S Weiss 1
PMCID: PMC175571  PMID: 9284184

Abstract

We have examined the human humoral immune response directed against proteins of Listeria monocytogenes in both healthy individuals and listeriosis patients. Two major targets for an antibody response were found in individuals that did not suffer from listeriosis: listeriolysin (Hly) and the recently described internalin-related protein (IrpA). In contrast, the humoral response in listeriosis patients appears to be more heterogeneous and included Hly, IrpA, InlB, and ActA as major targets.

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Selected References

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