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Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 2004 Jan;89(1):52–53. doi: 10.1136/adc.2002.017780

The progression of maternal RSV antibodies in the offspring

M Hacimustafaoglu 1, S Celebi 1, E Aynaci 1, M Sinirtas 1, N Koksal 1, A Kucukerdogan 1, I Ercan 1, G Goral 1, I Ildirim 1
PMCID: PMC1755925  PMID: 14709507

Abstract

At birth, 41 mothers (83%) tested positive for anti-RSV IgG and all of their babies carried maternal anti-RSV IgG. Anti-RSV IgG positivity dropped to 73% at 1 month, 6% at 3 months, and 2% at 6 months.

Between 3 and 6 months, 8% did acquire RSV infection, half of them as acute bronchiolitis and half as non-specific respiratory infection. All of the patients who acquired clinical RSV disease had an antibody concentration of <20 RU/ml which may be the cut off value for protection.

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