Abstract
OBJECTIVES: To investigate the mortality of workers who had been exposed to asbestos, machining fluids and foundry work in a foundry and heavy engineering plant in the railway rolling stock manufacturing industry in New Zealand. METHODS: Historical cohort study design. RESULTS: For the total workforce of 3522 men employed between 1945 and 1991, follow up was 90% of person-years to 31 December 1991. Significantly increased standardised mortality ratios (SMRs) were found for all causes of death combined (SMR 1.07; 95% confidence interval (95% CI) 1.01 to 1.14), all malignancies (SMR 1.15; 95% CI 1.01 to 1.31), circulatory (SMR 1.16; 95% CI 1.07 to 1.27) and musculoskeletal diseases (SMR 3.06; 95% CI 1.39 to 5.84), all digestive cancers (SMR 1.29; 95% CI 1.04 to 1.59), all respiratory cancers (SMR 1.34; 95% CI 1.08 to 1.65), cancer of the oesophagus (SMR 1.97; 95% CI 1.01 to 3.45), and mesothelioma of the pleura (SMR 6.58; 95% CI 1.24 to 19.49). Three deaths from pleural mesothelioma were recorded, with latency times of 51, 53, and 57 years. There were no dose-response relations between exposure to asbestos, machining fluids or foundry work, or by duration of employment in the plant, and any cause of death. CONCLUSIONS: This study found small increases in risk for several causes of death among foundry and heavy engineering workers; however, these increases were small and the possible effects of smoking and other lifestyle factors could not be excluded. There was evidence of asbestos related disease in those involved in engineering work in the past.
Full Text
The Full Text of this article is available as a PDF (101.9 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Andjelkovich D. A., Mathew R. M., Richardson R. B., Levine R. J. Mortality of iron foundry workers: I. Overall findings. J Occup Med. 1990 Jun;32(6):529–540. doi: 10.1097/00043764-199006000-00010. [DOI] [PubMed] [Google Scholar]
- Decoufle P. Further analysis of cancer mortality patterns among workers exposed to cutting oil mists. J Natl Cancer Inst. 1978 Oct;61(4):1025–1030. [PubMed] [Google Scholar]
- Eisen E. A., Tolbert P. E., Monson R. R., Smith T. J. Mortality studies of machining fluid exposure in the automobile industry I: A standardized mortality ratio analysis. Am J Ind Med. 1992;22(6):809–824. doi: 10.1002/ajim.4700220604. [DOI] [PubMed] [Google Scholar]
- Hansen E. S. A cohort mortality study of foundry workers. Am J Ind Med. 1997 Sep;32(3):223–233. doi: 10.1002/(sici)1097-0274(199709)32:3<223::aid-ajim7>3.0.co;2-y. [DOI] [PubMed] [Google Scholar]
- Hansen E. S. Cancer mortality among Danish molders. Am J Ind Med. 1991;20(3):401–409. doi: 10.1002/ajim.4700200312. [DOI] [PubMed] [Google Scholar]
- Järvholm B., Lavenius B. Mortality and cancer morbidity in workers exposed to cutting fluids. Arch Environ Health. 1987 Nov-Dec;42(6):361–366. doi: 10.1080/00039896.1987.9934360. [DOI] [PubMed] [Google Scholar]
- Koskela R. S., Hernberg S., Kärävä R., Järvinen E., Nurminen M. A mortality study of foundry workers. Scand J Work Environ Health. 1976;2 (Suppl 1):73–89. doi: 10.5271/sjweh.2829. [DOI] [PubMed] [Google Scholar]
- Mancuso T. F. Relative risk of mesothelioma among railroad machinists exposed to chrysotile. Am J Ind Med. 1988;13(6):639–657. doi: 10.1002/ajim.4700130604. [DOI] [PubMed] [Google Scholar]
- Mancuso T. F. Relative risk of mesothelioma among railroad machinists exposed to chrysotile. Am J Ind Med. 1988;13(6):639–657. doi: 10.1002/ajim.4700130604. [DOI] [PubMed] [Google Scholar]
- Ohlson C. G., Klaesson B., Hogstedt C. Mortality among asbestos-exposed workers in a railroad workshop. Scand J Work Environ Health. 1984 Oct;10(5):283–291. doi: 10.5271/sjweh.2329. [DOI] [PubMed] [Google Scholar]
- Pearce N., Prior I., Methven D., Culling C., Marshall S., Auld J., de Boer G., Bethwaite P. Follow up of New Zealand participants in British atmospheric nuclear weapons tests in the Pacific. BMJ. 1990 May 5;300(6733):1161–1166. doi: 10.1136/bmj.300.6733.1161. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Peto J., Doll R., Hermon C., Binns W., Clayton R., Goffe T. Relationship of mortality to measures of environmental asbestos pollution in an asbestos textile factory. Ann Occup Hyg. 1985;29(3):305–355. doi: 10.1093/annhyg/29.3.305. [DOI] [PubMed] [Google Scholar]
- Rosenman K. D., Reilly M. J., Kalinowski D. Work-related asthma and respiratory symptoms among workers exposed to metal-working fluids. Am J Ind Med. 1997 Oct;32(4):325–331. doi: 10.1002/(sici)1097-0274(199710)32:4<325::aid-ajim1>3.0.co;2-t. [DOI] [PubMed] [Google Scholar]
- Selikoff I. J. Use of death certificates in epidemiological studies, including occupational hazards: discordance with clinical and autopsy findings. Am J Ind Med. 1992;22(4):469–480. doi: 10.1002/ajim.4700220402. [DOI] [PubMed] [Google Scholar]
- Sorahan T., Faux A. M., Cooke M. A. Mortality among a cohort of United Kingdom steel foundry workers with special reference to cancers of the stomach and lung, 1946-90. Occup Environ Med. 1994 May;51(5):316–322. doi: 10.1136/oem.51.5.316. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sprince N. L., Thorne P. S., Popendorf W., Zwerling C., Miller E. R., DeKoster J. A. Respiratory symptoms and lung function abnormalities among machine operators in automobile production. Am J Ind Med. 1997 Apr;31(4):403–413. doi: 10.1002/(sici)1097-0274(199704)31:4<403::aid-ajim5>3.0.co;2-w. [DOI] [PubMed] [Google Scholar]
- Swanson G. M., Belle S. H. Cancer morbidity among woodworkers in the U.S. automotive industry. J Occup Med. 1982 Apr;24(4):315–319. [PubMed] [Google Scholar]
- Tilley B. C., Johnson C. C., Schultz L. R., Buffler P. A., Joseph C. L. Risk of colorectal cancer among automotive pattern and model makers. J Occup Med. 1990 Jun;32(6):541–546. doi: 10.1097/00043764-199006000-00011. [DOI] [PubMed] [Google Scholar]
- Tolbert P. E., Eisen E. A., Pothier L. J., Monson R. R., Hallock M. F., Smith T. J. Mortality studies of machining-fluid exposure in the automobile industry. II. Risks associated with specific fluid types. Scand J Work Environ Health. 1992 Dec;18(6):351–360. doi: 10.5271/sjweh.1562. [DOI] [PubMed] [Google Scholar]