Skip to main content
Sexually Transmitted Infections logoLink to Sexually Transmitted Infections
. 1999 Dec;75(6):385–388. doi: 10.1136/sti.75.6.385

Impact of HIV on adult (15-54) mortality in London: 1979-96

M Hickman, M Bardsley, D De Angelis, H Ward
PMCID: PMC1758260  PMID: 10754940

Abstract

OBJECTIVE: To describe the impact of HIV on mortality in men and women aged 15-54 in London. DESIGN: Combination of routine mortality statistics with reports of AIDS deaths adjusted for underreporting and change in address from time of report to time of death. Calculation of standardised mortality ratios (SMRs) for males including and excluding HIV comparing inner London and outer London with the rest of England and Wales. METHODS: Comparison of trends in all cause mortality and SMRs in males over time. Comparison of trends in HIV related deaths with other main causes of deaths in males and females in London. RESULTS: Age standardised rates for the rest of England and Wales showed a continual decline from 1979 to 1996 but rates in inner London males (ages 15-54) stopped declining around 1984-5 leading to a considerable increase in the SMR for inner London from 127 for 1985-7 to 171 for 1994-6. SMRs excluding HIV related deaths for inner London, however, showed no significant change over this time. There was a fall in HIV related mortality in 1996, though HIV was still the leading cause of death in males and second leading cause of death in females in inner London, and the fourth commonest cause of death in males in outer London. CONCLUSION: These data are the first to indicate the impact of HIV on mortality within a significant population in England and Wales. They show that public health priorities in London are different from the rest of the country. Analyses of trends of all cause mortality in people under 65 may mislead unless they take account of HIV. 




Full Text

The Full Text of this article is available as a PDF (103.3 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aldous J., Hickman M., Ellam A., Gazzard B., Hargreaves S. Impact of HIV infection on mortality in young men in a London health authority. BMJ. 1992 Jul 25;305(6847):219–221. doi: 10.1136/bmj.305.6847.219. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Casabona Barbarà J., Blanch Mur C., Vall Mayans M., Salvador Vilalta X. Premature mortality related to AIDS among men and women in Catalonia. AIDS. 1993 Aug;7(8):1099–1103. doi: 10.1097/00002030-199308000-00012. [DOI] [PubMed] [Google Scholar]
  3. Charlton J. Which areas are healthiest? Popul Trends. 1996 Spring;(83):17–24. [PubMed] [Google Scholar]
  4. Coates T. J., Aggleton P., Gutzwiller F., Des Jarlais D., Kihara M., Kippax S., Schechter M., van den Hoek J. A. HIV prevention in developed countries. Lancet. 1996 Oct 26;348(9035):1143–1148. doi: 10.1016/s0140-6736(96)02307-0. [DOI] [PubMed] [Google Scholar]
  5. Conti S., Farchi G., Prati S. AIDS as a leading cause of death among young adults in Italy. Eur J Epidemiol. 1994 Dec;10(6):669–673. doi: 10.1007/BF01719279. [DOI] [PubMed] [Google Scholar]
  6. Conti S., Lepri A. C., Farchi G., Napoli P. A., Prati S., Rezza G. AIDS: a major health problem among young Italian women. AIDS. 1996 Apr;10(4):407–411. [PubMed] [Google Scholar]
  7. Gregson S., Garnett G. P., Anderson R. M. Is HIV-1 likely to become a leading cause of adult mortality in sub-Saharan Africa? J Acquir Immune Defic Syndr. 1994 Aug;7(8):839–852. [PubMed] [Google Scholar]
  8. Hickman M., Aldous J., Gazzard B., Ellam A. AIDS surveillance: a direct assessment of under-reporting. AIDS. 1993 Dec;7(12):1661–1665. doi: 10.1097/00002030-199312000-00018. [DOI] [PubMed] [Google Scholar]
  9. Hogg R. S., O'Shaughnessy M. V., Gataric N., Yip B., Craib K., Schechter M. T., Montaner J. S. Decline in deaths from AIDS due to new antiretrovirals. Lancet. 1997 May 3;349(9061):1294–1294. doi: 10.1016/S0140-6736(05)62505-6. [DOI] [PubMed] [Google Scholar]
  10. King M. B. AIDS on the death certificate: the final stigma. BMJ. 1989 Mar 18;298(6675):734–736. doi: 10.1136/bmj.298.6675.734. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. McCormick A. Unrecognised HIV related deaths. BMJ. 1991 Jun 8;302(6789):1365–1367. doi: 10.1136/bmj.302.6789.1365. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Murray C. J., Lopez A. D. Mortality by cause for eight regions of the world: Global Burden of Disease Study. Lancet. 1997 May 3;349(9061):1269–1276. doi: 10.1016/S0140-6736(96)07493-4. [DOI] [PubMed] [Google Scholar]
  13. Raleigh V. S., Kiri V. A. Life expectancy in England: variations and trends by gender, health authority, and level of deprivation. J Epidemiol Community Health. 1997 Dec;51(6):649–658. doi: 10.1136/jech.51.6.649. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Selik R. M., Chu S. Y., Buehler J. W. HIV infection as leading cause of death among young adults in US cities and states. JAMA. 1993 Jun 16;269(23):2991–2994. [PubMed] [Google Scholar]

Articles from Sexually Transmitted Infections are provided here courtesy of BMJ Publishing Group

RESOURCES