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. 1997 Aug;52(8):671–673. doi: 10.1136/thx.52.8.671

Should patients with cystic fibrosis infected with Burkholderia cepacia undergo lung transplantation?

A K Webb, J Egan
PMCID: PMC1758623  PMID: 9337823

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Selected References

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  1. Butler S. L., Doherty C. J., Hughes J. E., Nelson J. W., Govan J. R. Burkholderia cepacia and cystic fibrosis: do natural environments present a potential hazard? J Clin Microbiol. 1995 Apr;33(4):1001–1004. doi: 10.1128/jcm.33.4.1001-1004.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Egan J. J., McNeil K., Bookless B., Gould K., Corris P., Higenbottam T., Webb A. K., Woodcock A. A. Post-transplantation survival of cystic fibrosis patients infected with Pseudomonas cepacia. Lancet. 1994 Aug 20;344(8921):552–553. doi: 10.1016/s0140-6736(94)91950-x. [DOI] [PubMed] [Google Scholar]
  3. Flume P. A., Egan T. M., Paradowski L. J., Detterbeck F. C., Thompson J. T., Yankaskas J. R. Infectious complications of lung transplantation. Impact of cystic fibrosis. Am J Respir Crit Care Med. 1994 Jun;149(6):1601–1607. doi: 10.1164/ajrccm.149.6.7516251. [DOI] [PubMed] [Google Scholar]
  4. Glass S., Govan J. R. Pseudomonas cepacia--fatal pulmonary infection in a patient with cystic fibrosis. J Infect. 1986 Sep;13(2):157–158. doi: 10.1016/s0163-4453(86)92953-1. [DOI] [PubMed] [Google Scholar]
  5. Govan J. R., Brown P. H., Maddison J., Doherty C. J., Nelson J. W., Dodd M., Greening A. P., Webb A. K. Evidence for transmission of Pseudomonas cepacia by social contact in cystic fibrosis. Lancet. 1993 Jul 3;342(8862):15–19. doi: 10.1016/0140-6736(93)91881-l. [DOI] [PubMed] [Google Scholar]
  6. Govan J. R., Hughes J. E., Vandamme P. Burkholderia cepacia: medical, taxonomic and ecological issues. J Med Microbiol. 1996 Dec;45(6):395–407. doi: 10.1099/00222615-45-6-395. [DOI] [PubMed] [Google Scholar]
  7. Harris John. What is the good of health care? Bioethics. 1996 Oct;10(4):269–291. doi: 10.1111/j.1467-8519.1996.tb00129.x. [DOI] [PubMed] [Google Scholar]
  8. Isles A., Maclusky I., Corey M., Gold R., Prober C., Fleming P., Levison H. Pseudomonas cepacia infection in cystic fibrosis: an emerging problem. J Pediatr. 1984 Feb;104(2):206–210. doi: 10.1016/s0022-3476(84)80993-2. [DOI] [PubMed] [Google Scholar]
  9. LiPuma J. J., Dasen S. E., Nielson D. W., Stern R. C., Stull T. L. Person-to-person transmission of Pseudomonas cepacia between patients with cystic fibrosis. Lancet. 1990 Nov 3;336(8723):1094–1096. doi: 10.1016/0140-6736(90)92571-x. [DOI] [PubMed] [Google Scholar]
  10. Muhdi K., Edenborough F. P., Gumery L., O'Hickey S., Smith E. G., Smith D. L., Stableforth D. E. Outcome for patients colonised with Burkholderia cepacia in a Birmingham adult cystic fibrosis clinic and the end of an epidemic. Thorax. 1996 Apr;51(4):374–377. doi: 10.1136/thx.51.4.374. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Nelson J. W., Butler S. L., Krieg D., Govan J. R. Virulence factors of Burkholderia cepacia. FEMS Immunol Med Microbiol. 1994 Feb;8(2):89–97. doi: 10.1111/j.1574-695X.1994.tb00430.x. [DOI] [PubMed] [Google Scholar]
  12. Noyes B. E., Michaels M. G., Kurland G., Armitage J. M., Orenstein D. M. Pseudomonas cepacia empyema necessitatis after lung transplantation in two patients with cystic fibrosis. Chest. 1994 Jun;105(6):1888–1891. doi: 10.1378/chest.105.6.1888. [DOI] [PubMed] [Google Scholar]
  13. Peckham D., Crouch S., Humphreys H., Lobo B., Tse A., Knox A. J. Effect of antibiotic treatment on inflammatory markers and lung function in cystic fibrosis patients with Pseudomonas cepacia. Thorax. 1994 Aug;49(8):803–807. doi: 10.1136/thx.49.8.803. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Pitt T. L., Kaufmann M. E., Patel P. S., Benge L. C., Gaskin S., Livermore D. M. Type characterisation and antibiotic susceptibility of Burkholderia (Pseudomonas) cepacia isolates from patients with cystic fibrosis in the United Kingdom and the Republic of Ireland. J Med Microbiol. 1996 Mar;44(3):203–210. doi: 10.1099/00222615-44-3-203. [DOI] [PubMed] [Google Scholar]
  15. Ramirez J. C., Patterson G. A., Winton T. L., de Hoyos A. L., Miller J. D., Maurer J. R. Bilateral lung transplantation for cystic fibrosis. The Toronto Lung Transplant Group. J Thorac Cardiovasc Surg. 1992 Feb;103(2):287–294. [PubMed] [Google Scholar]
  16. Smith D. L., Gumery L. B., Smith E. G., Stableforth D. E., Kaufmann M. E., Pitt T. L. Epidemic of Pseudomonas cepacia in an adult cystic fibrosis unit: evidence of person-to-person transmission. J Clin Microbiol. 1993 Nov;31(11):3017–3022. doi: 10.1128/jcm.31.11.3017-3022.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Snell G. I., de Hoyos A., Krajden M., Winton T., Maurer J. R. Pseudomonas cepacia in lung transplant recipients with cystic fibrosis. Chest. 1993 Feb;103(2):466–471. doi: 10.1378/chest.103.2.466. [DOI] [PubMed] [Google Scholar]
  18. Sylvester F. A., Sajjan U. S., Forstner J. F. Burkholderia (basonym Pseudomonas) cepacia binding to lipid receptors. Infect Immun. 1996 Apr;64(4):1420–1425. doi: 10.1128/iai.64.4.1420-1425.1996. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Tablan O. C., Chorba T. L., Schidlow D. V., White J. W., Hardy K. A., Gilligan P. H., Morgan W. M., Carson L. A., Martone W. J., Jason J. M. Pseudomonas cepacia colonization in patients with cystic fibrosis: risk factors and clinical outcome. J Pediatr. 1985 Sep;107(3):382–387. doi: 10.1016/s0022-3476(85)80511-4. [DOI] [PubMed] [Google Scholar]
  20. Thomassen M. J., Demko C. A., Klinger J. D., Stern R. C. Pseudomonas cepacia colonization among patients with cystic fibrosis. A new opportunist. Am Rev Respir Dis. 1985 May;131(5):791–796. doi: 10.1164/arrd.1985.131.5.791. [DOI] [PubMed] [Google Scholar]
  21. Whiteford M. L., Wilkinson J. D., McColl J. H., Conlon F. M., Michie J. R., Evans T. J., Paton J. Y. Outcome of Burkholderia (Pseudomonas) cepacia colonisation in children with cystic fibrosis following a hospital outbreak. Thorax. 1995 Nov;50(11):1194–1198. doi: 10.1136/thx.50.11.1194. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Yamagishi Y., Fujita J., Takigawa K., Negayama K., Nakazawa T., Takahara J. Clinical features of Pseudomonas cepacia pneumonia in an epidemic among immunocompromised patients. Chest. 1993 Jun;103(6):1706–1709. doi: 10.1378/chest.103.6.1706. [DOI] [PubMed] [Google Scholar]

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