Abstract
BACKGROUND: Primary spontaneous pneumothorax (PSP) is a common clinical problem and its incidence is thought to be increasing. The risk of recurrence is high and various studies quote rates of 20-60%. Factors which may or may not predispose to recurrence have not yet been established. METHODS: In a study period of four years 291 cases with a diagnosis of pneumothorax were reviewed; 153 patients with PSP were included in the study. Their risk of recurrence was analysed with particular reference to the following variables: age, sex, height and body mass index (BMI) of the patient, the initial size of pneumothorax, the smoking status of the patient, and the primary form of treatment employed. Univariate analysis was carried out by chi 2 testing and multivariate analysis was calculated by a logistic regression model. RESULTS: A retrospective study of 275 episodes of PSP in 153 patients over a four year period confirmed a high incidence of recurrence (54.2%). PSP was twice as common in men as in women, though women were significantly more likely to develop a recurrence (chi 2 = 7.58, df = 1, p < 0.01). Male height was the second most important factor, and smoking cessation the only other variable which significantly influenced the risk of recurrence. CONCLUSIONS: Analysis of several potential risk factors revealed that recurrence was not related to the BMI of the patient, the initial treatment of the pneumothorax, nor to its size. Recurrence was more common in taller men and in women. Smoking cessation appeared to reduce the risk of recurrence. These findings are discussed in the context of the possible aetiology of spontaneous pneumothorax, recurrences, and the management thereof.
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Selected References
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- Bense L., Eklund G., Wiman L. G. Bilateral bronchial anomaly. A pathogenetic factor in spontaneous pneumothorax. Am Rev Respir Dis. 1992 Aug;146(2):513–516. doi: 10.1164/ajrccm/146.2.513. [DOI] [PubMed] [Google Scholar]
- Bense L., Eklund G., Wiman L. G. Smoking and the increased risk of contracting spontaneous pneumothorax. Chest. 1987 Dec;92(6):1009–1012. doi: 10.1378/chest.92.6.1009. [DOI] [PubMed] [Google Scholar]
- Berkman N., Bar-Ziv J., Breuer R. Recurrent spontaneous pneumothorax associated with bronchial atresia. Respir Med. 1996 May;90(5):307–309. doi: 10.1016/s0954-6111(96)90102-x. [DOI] [PubMed] [Google Scholar]
- Harvey J., Prescott R. J. Simple aspiration versus intercostal tube drainage for spontaneous pneumothorax in patients with normal lungs. British Thoracic Society Research Committee. BMJ. 1994 Nov 19;309(6965):1338–1339. doi: 10.1136/bmj.309.6965.1338. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ito H., Aviado D. M. Prevention of pulmonary emphysema in rats by progesterone. J Pharmacol Exp Ther. 1968 Jun;161(2):197–204. [PubMed] [Google Scholar]
- Light R. W. Management of spontaneous pneumothorax. Am Rev Respir Dis. 1993 Jul;148(1):245–248. doi: 10.1164/ajrccm/148.1.245. [DOI] [PubMed] [Google Scholar]
- Lippert H. L., Lund O., Blegvad S., Larsen H. V. Independent risk factors for cumulative recurrence rate after first spontaneous pneumothorax. Eur Respir J. 1991 Mar;4(3):324–331. [PubMed] [Google Scholar]
- Miller A. C., Harvey J. E. Guidelines for the management of spontaneous pneumothorax. Standards of Care Committee, British Thoracic Society. BMJ. 1993 Jul 10;307(6896):114–116. doi: 10.1136/bmj.307.6896.114. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nakamura H., Konishiike J., Sugamura A., Takeno Y. Epidemiology of spontaneous pneumothorax in women. Chest. 1986 Mar;89(3):378–382. doi: 10.1378/chest.89.3.378. [DOI] [PubMed] [Google Scholar]
- Neal J. F., Vargas G., Smith D. E., Akl B. F., Edwards W. S. Bilateral bleb excision through median sternotomy. Am J Surg. 1979 Dec;138(6):794–797. doi: 10.1016/0002-9610(79)90298-8. [DOI] [PubMed] [Google Scholar]
- Primrose W. R. Spontaneous pneumothorax: a retrospective review of aetiology, pathogenesis and management. Scott Med J. 1984 Jan;29(1):15–20. doi: 10.1177/003693308402900105. [DOI] [PubMed] [Google Scholar]
- Ruckley C. V., McCormack R. J. The management of spontaneous pneumothorax. Thorax. 1966 Mar;21(2):139–144. doi: 10.1136/thx.21.2.139. [DOI] [PMC free article] [PubMed] [Google Scholar]
- West J. B. Distribution of mechanical stress in the lung, a possible factor in localisation of pulmonary disease. Lancet. 1971 Apr 24;1(7704):839–841. doi: 10.1016/s0140-6736(71)91501-7. [DOI] [PubMed] [Google Scholar]
