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. 1988 Oct;32(10):1598–1599. doi: 10.1128/aac.32.10.1598

High-level resistance to trimethoprim in Shigella sonnei associated with plasmid-encoded dihydrofolate reductase type I.

R Delgado 1, J R Otero 1
PMCID: PMC175929  PMID: 3056243

Abstract

By DNA hybridization, the gene encoding dihydrofolate reductase type I was found in 58 of 59 highly trimethoprim-resistant clinical isolates of Shigella sonnei obtained from 1981 through 1987 in Madrid, Spain. No strain harbored the type II gene. In selected strains, the type I gene was demonstrated to be in a plasmid.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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