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. 1988 Nov;32(11):1603–1608. doi: 10.1128/aac.32.11.1603

Bacterial adhesion: modulation by antibiotics which perturb protein synthesis.

D M Schifferli 1, E H Beachey 1
PMCID: PMC175936  PMID: 3075432

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abraham S. N., Beachey E. H., Simpson W. A. Adherence of streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa to fibronectin-coated and uncoated epithelial cells. Infect Immun. 1983 Sep;41(3):1261–1268. doi: 10.1128/iai.41.3.1261-1268.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Atkinson B. A., Amaral L. Sublethal concentrations of antibiotics, effects on bacteria and the immune system. Crit Rev Microbiol. 1982;9(2):101–138. doi: 10.3109/10408418209104487. [DOI] [PubMed] [Google Scholar]
  3. Bassaris H. P., Lianou P. E., Papavassiliou J. T. Interaction of subminimal inhibitory concentrations of clindamycin and Escherichia coli: effects on adhesion and polymorphonuclear leukocyte function. J Antimicrob Chemother. 1984 Apr;13(4):361–367. doi: 10.1093/jac/13.4.361. [DOI] [PubMed] [Google Scholar]
  4. Beachey E. H. Bacterial adherence: adhesin-receptor interactions mediating the attachment of bacteria to mucosal surface. J Infect Dis. 1981 Mar;143(3):325–345. doi: 10.1093/infdis/143.3.325. [DOI] [PubMed] [Google Scholar]
  5. Båga M., Norgren M., Normark S. Biogenesis of E. coli Pap pili: papH, a minor pilin subunit involved in cell anchoring and length modulation. Cell. 1987 Apr 24;49(2):241–251. doi: 10.1016/0092-8674(87)90565-4. [DOI] [PubMed] [Google Scholar]
  6. Chabanon G., Archambaud M., Marty N., Enjalbert L. Hémagglutinines et adhésines des Escherichia coli isolés des urines. Effet inhibiteur du chlorhydrate de tétracycline, de doxycycline et de minocycline à concentrations sub-inhibitrices. Résultats préliminaires. Pathol Biol (Paris) 1982 Jun;30(6 Pt 2):543–548. [PubMed] [Google Scholar]
  7. Chopra I., Ball P. Transport of antibiotics into bacteria. Adv Microb Physiol. 1982;23:183–240. doi: 10.1016/s0065-2911(08)60338-0. [DOI] [PubMed] [Google Scholar]
  8. Chopra I., Hacker K. Inhibition of K88-mediated adhesion of Escherichia coli to mammalian receptors by antibiotics that affect bacterial protein synthesis. J Antimicrob Chemother. 1986 Oct;18(4):441–451. doi: 10.1093/jac/18.4.441. [DOI] [PubMed] [Google Scholar]
  9. Chopra I., Howe T. G. Bacterial resistance to the tetracyclines. Microbiol Rev. 1978 Dec;42(4):707–724. doi: 10.1128/mr.42.4.707-724.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Chopra I., Linton A. The antibacterial effects of low concentrations of antibiotics. Adv Microb Physiol. 1986;28:211–259. doi: 10.1016/s0065-2911(08)60240-4. [DOI] [PubMed] [Google Scholar]
  11. Christensen G. D., Beachey E. H. The molecular basis for the localization of bacterial infections. Adv Intern Med. 1984;30:79–112. [PubMed] [Google Scholar]
  12. Cleveland R. F., Holtje J. V., Wicken A. J., Tomasz A., Daneo-Moore L., Shockman G. D. Inhibition of bacterial wall lysins by lipoteichoic acids and related compounds. Biochem Biophys Res Commun. 1975 Dec 1;67(3):1128–1135. doi: 10.1016/0006-291x(75)90791-3. [DOI] [PubMed] [Google Scholar]
  13. Davis B. D. Mechanism of bactericidal action of aminoglycosides. Microbiol Rev. 1987 Sep;51(3):341–350. doi: 10.1128/mr.51.3.341-350.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. De Graaf F. K., Mooi F. R. The fimbrial adhesins of Escherichia coli. Adv Microb Physiol. 1986;28:65–143. doi: 10.1016/s0065-2911(08)60237-4. [DOI] [PubMed] [Google Scholar]
  15. Deneke C. F., Thorne G. M., Larson A. D., Gorbach S. L. Effect of tetracycline on the attachment of K88+ enterotoxigenic Escherichia coli to porcine small-intestinal cells. J Infect Dis. 1985 Nov;152(5):1032–1036. doi: 10.1093/infdis/152.5.1032. [DOI] [PubMed] [Google Scholar]
  16. Doran J. E. Influence of antibiotics on fibronectin binding and phagocytosis of staphylococci by human polymorphonuclear leukocytes. Eur J Clin Microbiol. 1987 Apr;6(2):196–198. doi: 10.1007/BF02018212. [DOI] [PubMed] [Google Scholar]
  17. Doran J. E., Rissing J. P. Influence of clindamycin on fibronectin-staphylococcal interactions. J Antimicrob Chemother. 1983 Oct;12 (Suppl 100):75–83. doi: 10.1093/jac/12.suppl_c.75. [DOI] [PubMed] [Google Scholar]
  18. Dougan G., Dowd G., Kehoe M. Organization of K88ac-encoded polypeptides in the Escherichia coli cell envelope: use of minicells and outer membrane protein mutants for studying assembly of pili. J Bacteriol. 1983 Jan;153(1):364–370. doi: 10.1128/jb.153.1.364-370.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Eisenstein B. I., Beachey E. H., Ofek I. Influence of sublethal concentrations of antibiotics on the expression of the mannose-specific ligand of Escherichia coli. Infect Immun. 1980 Apr;28(1):154–159. doi: 10.1128/iai.28.1.154-159.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Eisenstein B. I., Ofek I., Beachey E. H. Interference with the mannose binding and epithelial cell adherence of Escherichia coli by sublethal concentrations of streptomycin. J Clin Invest. 1979 Jun;63(6):1219–1228. doi: 10.1172/JCI109417. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Eisenstein B. I., Ofek I., Beachey E. H. Loss of lectin-like activity in aberrant type 1 fimbriae of Escherichia coli. Infect Immun. 1981 Feb;31(2):792–797. doi: 10.1128/iai.31.2.792-797.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Falkowski W., Edwards M., Schaeffer A. J. Inhibitory effect of substituted aromatic hydrocarbons on adherence of Escherichia coli to human epithelial cells. Infect Immun. 1986 Jun;52(3):863–866. doi: 10.1128/iai.52.3.863-866.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Firon N., Ashkenazi S., Mirelman D., Ofek I., Sharon N. Aromatic alpha-glycosides of mannose are powerful inhibitors of the adherence of type 1 fimbriated Escherichia coli to yeast and intestinal epithelial cells. Infect Immun. 1987 Feb;55(2):472–476. doi: 10.1128/iai.55.2.472-476.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Flock J. I., Fröman G., Jönsson K., Guss B., Signäs C., Nilsson B., Raucci G., Hök M., Wadström T., Lindberg M. Cloning and expression of the gene for a fibronectin-binding protein from Staphylococcus aureus. EMBO J. 1987 Aug;6(8):2351–2357. doi: 10.1002/j.1460-2075.1987.tb02511.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Forestier C., Darfeuille-Michaud A., Joly B. Effects of antibiotics on adhesion of enterotoxigenic Escherichia coli strains. Eur J Clin Microbiol. 1984 Oct;3(5):427–432. doi: 10.1007/BF02017364. [DOI] [PubMed] [Google Scholar]
  26. Francioli P., Glauser M. P. Successful prophylaxis of experimental streptococcal endocarditis with single doses of sublethal concentrations of penicillin. J Antimicrob Chemother. 1985 Jan;15 (Suppl A):297–302. doi: 10.1093/jac/15.suppl_a.297. [DOI] [PubMed] [Google Scholar]
  27. Geers T. A., Baker N. R. The effect of sublethal concentrations of aminoglycosides on adherence of Pseudomonas aeruginosa to hamster tracheal epithelium. J Antimicrob Chemother. 1987 May;19(5):561–568. doi: 10.1093/jac/19.5.561. [DOI] [PubMed] [Google Scholar]
  28. Gilsdorf J. R., Jesperson J. M. Effect of antibiotics on adherence of Haemophilus influenzae type b. Antimicrob Agents Chemother. 1986 Sep;30(3):370–374. doi: 10.1128/aac.30.3.370. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Giudicelli S., Tomasz A. Attachment of pneumococcal autolysin to wall teichoic acids, an essential step in enzymatic wall degradation. J Bacteriol. 1984 Jun;158(3):1188–1190. doi: 10.1128/jb.158.3.1188-1190.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Hales B. A., Amyes S. G. The effect of a range of antimicrobial drugs on the haemagglutination of two clinical isolates from urinary tract infections. J Antimicrob Chemother. 1985 Nov;16(5):671–674. doi: 10.1093/jac/16.5.671. [DOI] [PubMed] [Google Scholar]
  31. Hirashima A., Childs G., Inouye M. Differential inhibitory effects of antibiotics on the biosynthesis of envelope proteins of Escherichia coli. J Mol Biol. 1973 Sep 15;79(2):373–389. doi: 10.1016/0022-2836(73)90012-0. [DOI] [PubMed] [Google Scholar]
  32. Jones G. W., Isaacson R. E. Proteinaceous bacterial adhesins and their receptors. Crit Rev Microbiol. 1983;10(3):229–260. doi: 10.3109/10408418209113564. [DOI] [PubMed] [Google Scholar]
  33. Klein U., Pawelzik M., Opferkuch W. Influence of beta-lactam antibiotics, fosfomycin and vancomycin on the adherence (hemagglutination) of Escherichia coli-containing different adhesins. Chemotherapy. 1985;31(2):138–145. doi: 10.1159/000238326. [DOI] [PubMed] [Google Scholar]
  34. Klemm P., Christiansen G. Three fim genes required for the regulation of length and mediation of adhesion of Escherichia coli type 1 fimbriae. Mol Gen Genet. 1987 Jul;208(3):439–445. doi: 10.1007/BF00328136. [DOI] [PubMed] [Google Scholar]
  35. Kristiansen B. E., Rustad L., Spanne O., Bjorvatn B. Effect of subminimal inhibitory concentrations of antimicrobial agents on the piliation and adherence of Neisseria meningitidis. Antimicrob Agents Chemother. 1983 Nov;24(5):731–734. doi: 10.1128/aac.24.5.731. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Lianou P. E., Bassaris H. P., Votta E. G., Papavassiliou J. T. Interaction of subminimal inhibitory concentrations of clindamycin and gram-negative aerobic organisms: effects on adhesion and polymorphonuclear leukocyte function. J Antimicrob Chemother. 1985 Apr;15(4):481–487. doi: 10.1093/jac/15.4.481. [DOI] [PubMed] [Google Scholar]
  37. Lund B., Lindberg F., Marklund B. I., Normark S. The PapG protein is the alpha-D-galactopyranosyl-(1----4)-beta-D-galactopyranose-binding adhesin of uropathogenic Escherichia coli. Proc Natl Acad Sci U S A. 1987 Aug;84(16):5898–5902. doi: 10.1073/pnas.84.16.5898. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Maurer L., Orndorff P. E. Identification and characterization of genes determining receptor binding and pilus length of Escherichia coli type 1 pili. J Bacteriol. 1987 Feb;169(2):640–645. doi: 10.1128/jb.169.2.640-645.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Minion F. C., Abraham S. N., Beachey E. H., Goguen J. D. The genetic determinant of adhesive function in type 1 fimbriae of Escherichia coli is distinct from the gene encoding the fimbrial subunit. J Bacteriol. 1986 Mar;165(3):1033–1036. doi: 10.1128/jb.165.3.1033-1036.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Mooi F. R., Wijfjes A., de Graaf F. K. Identification and characterization of precursors in the biosynthesis of the K88ab fimbria of Escherichia coli. J Bacteriol. 1983 Apr;154(1):41–49. doi: 10.1128/jb.154.1.41-49.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Nealon T. J., Beachey E. H., Courtney H. S., Simpson W. A. Release of fibronectin-lipoteichoic acid complexes from group A streptococci with penicillin. Infect Immun. 1986 Feb;51(2):529–535. doi: 10.1128/iai.51.2.529-535.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  42. Nikaido H., Vaara M. Molecular basis of bacterial outer membrane permeability. Microbiol Rev. 1985 Mar;49(1):1–32. doi: 10.1128/mr.49.1.1-32.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Ofek I., Beachey E. H., Eisenstein B. I., Alkan M. L., Sharon N. Suppression of bacterial adherence by subminimal inhibitory concentrations of beta-lactam and aminoglycoside antibiotics. Rev Infect Dis. 1979 Sep-Oct;1(5):832–837. doi: 10.1093/clinids/1.5.832. [DOI] [PubMed] [Google Scholar]
  44. Ogaard A. R., Bjøro K., Bukholm G., Berdal B. P. Pseudomonas aeruginosa virulence factors: modifications by sub-inhibitory concentrations of carbenicillin or gentamicin. Acta Pathol Microbiol Immunol Scand B. 1986 Apr;94(2):63–68. doi: 10.1111/j.1699-0463.1986.tb03021.x. [DOI] [PubMed] [Google Scholar]
  45. Pato M. L. Tetracycline inhibits propagation of deoxyribonucleic acid replication and alters membrane properties. Antimicrob Agents Chemother. 1977 Feb;11(2):318–323. doi: 10.1128/aac.11.2.318. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Peros W. J., Etherden I., Gibbons R. J., Skobe Z. Alteration of fimbriation and cell hydrophobicity by sublethal concentrations of tetracycline. J Periodontal Res. 1985 Jan;20(1):24–30. doi: 10.1111/j.1600-0765.1985.tb00406.x. [DOI] [PubMed] [Google Scholar]
  47. Peros W. J., Gibbons R. J. Influence of sublethal antibiotic concentrations on bacterial adherence to saliva-treated hydroxyapatite. Infect Immun. 1982 Jan;35(1):326–334. doi: 10.1128/iai.35.1.326-334.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  48. Piovant M., Varenne S., Pagès J. M., Lazdunski C. Preferential sensitivity of syntheses of exported proteins to translation inhibitors of low polarity in Escherichia coli. Mol Gen Genet. 1978 Sep 8;164(3):265–274. doi: 10.1007/BF00333156. [DOI] [PubMed] [Google Scholar]
  49. Proctor R. A., Olbrantz P. J., Mosher D. F. Subinhibitory concentrations of antibiotics alter fibronectin binding to Staphylococcus aureus. Antimicrob Agents Chemother. 1983 Nov;24(5):823–826. doi: 10.1128/aac.24.5.823. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Randall L. L., Hardy S. J. Synthesis of exported proteins by membrane-bound polysomes from Escherichia coli. Eur J Biochem. 1977 May 2;75(1):43–53. doi: 10.1111/j.1432-1033.1977.tb11502.x. [DOI] [PubMed] [Google Scholar]
  51. Redjeb S. B., Slim A., Horchani A., Zmerilli S., Boujnah A., Lorian V. Effects of ten milligrams of ampicillin per day on urinary tract infections. Antimicrob Agents Chemother. 1982 Dec;22(6):1084–1086. doi: 10.1128/aac.22.6.1084. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Roland F., Heelan J. L'hémagglutination par Escherichia coli en présence d'antibiotiques: le phénomène d'inhibition. Ann Microbiol (Paris) 1979 Jul;130B(1):33–42. [PubMed] [Google Scholar]
  53. Salit I. E. Effect of subinhibitory concentrations of antimicrobials on meningococcal adherence. Can J Microbiol. 1983 Mar;29(3):369–376. doi: 10.1139/m83-061. [DOI] [PubMed] [Google Scholar]
  54. Sandberg T., Stenqvist K., Svanborg-Edén C. Effects of subminimal inhibitory concentrations of ampicillin, chloramphenicol, and nitrofurantoin on the attachment of Escherichia coli to human uroepithelial cells in vitro. Rev Infect Dis. 1979 Sep-Oct;1(5):838–844. doi: 10.1093/clinids/1.5.838. [DOI] [PubMed] [Google Scholar]
  55. Schadow K. H., Simpson W. A., Christensen G. D. Characteristics of adherence to plastic tissue culture plates of coagulase-negative staphylococci exposed to subinhibitory concentrations of antimicrobial agents. J Infect Dis. 1988 Jan;157(1):71–77. doi: 10.1093/infdis/157.1.71. [DOI] [PubMed] [Google Scholar]
  56. Schifferli D. M., Beachey E. H. Bacterial adhesion: modulation by antibiotics with primary targets other than protein synthesis. Antimicrob Agents Chemother. 1988 Nov;32(11):1609–1613. doi: 10.1128/aac.32.11.1609. [DOI] [PMC free article] [PubMed] [Google Scholar]
  57. Shibl A. M. Effect of antibiotics on adherence of microorganisms to epithelial cell surfaces. Rev Infect Dis. 1985 Jan-Feb;7(1):51–65. doi: 10.1093/clinids/7.1.51. [DOI] [PubMed] [Google Scholar]
  58. Stephens D. S., Krebs J. W., McGee Z. A. Loss of pili and decreased attachment to human cells by Neisseria meningitidis and Neisseria gonorrhoeae exposed to subinhibitory concentrations of antibiotics. Infect Immun. 1984 Nov;46(2):507–513. doi: 10.1128/iai.46.2.507-513.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  59. Sugarman B., Donta S. T. Effect of antibiotics on the adherence of enterobacteriaceae to human buccal cells. J Infect Dis. 1979 Oct;140(4):622–625. doi: 10.1093/infdis/140.4.622. [DOI] [PubMed] [Google Scholar]
  60. Søgaard H., Larsen J. L. The effect of antibiotics on mannose-resistant haemagglutination by K88- and K99-positive Escherichia coli strains. J Vet Pharmacol Ther. 1983 Sep;6(3):187–193. doi: 10.1111/j.1365-2885.1983.tb00463.x. [DOI] [PubMed] [Google Scholar]
  61. Tylewska S., Hjertén S., Wadström T. Effect of subinhibitory concentrations of antibiotics on the adhesion of Streptococcus pyogenes to pharyngeal epithelial cells. Antimicrob Agents Chemother. 1981 Nov;20(5):563–566. doi: 10.1128/aac.20.5.563. [DOI] [PMC free article] [PubMed] [Google Scholar]
  62. Vishwanath S., Guay C. M., Ramphal R. Effects of subminimal inhibitory concentrations of antibiotics on the adherence of Pseudomonas aeruginosa to tracheobronchial mucin. J Antimicrob Chemother. 1987 May;19(5):579–583. doi: 10.1093/jac/19.5.579. [DOI] [PubMed] [Google Scholar]
  63. Vosbeck K., Mett H., Huber U., Bohn J., Petignat M. Effects of low concentrations of antibiotics on Escherichia coli adhesion. Antimicrob Agents Chemother. 1982 Jun;21(6):864–869. doi: 10.1128/aac.21.6.864. [DOI] [PMC free article] [PubMed] [Google Scholar]

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