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. 1985 Feb;27(2):277–279. doi: 10.1128/aac.27.2.277

Activities of arabinosyladenine monophosphate and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against ground squirrel hepatitis virus in vivo as determined by reduction in serum virion-associated DNA polymerase.

D F Smee, S S Knight, A E Duke, W S Robinson, T R Matthews, P L Marion
PMCID: PMC176255  PMID: 2580482

Abstract

Treatment of chronic ground squirrel hepatitis virus infection with arabinosyladenine monophosphate at 20 mg/kg per day for 3 weeks caused marked decreases in serum virion-associated DNA polymerase concentrations in three of five squirrels. Statistically significant but less dramatic decreases in enzymatic activity were noted in two of six squirrels treated with 50 mg of 9-(1,3-dihydroxy-2-propoxymethyl)guanine per kg per day. After therapy, DNA polymerase activities rose to pretreatment levels.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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