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. 1975 May;27(3):410–418.

Age trends in human chiasma frequencies and recombination fractions. I. Chiasma frequencies.

K Lange 1, B M Page 1, R C Elston 1
PMCID: PMC1762862  PMID: 803020

Abstract

Chiasma frequency data on 183 males were subjected to an analysis of covariance. There appeared to be little or no linear trend in chiasma frequency with age. This conclusion was supported by a detailed analysis of chiasma frequencies for each autosome from 21 males. There were, however, significant differences among investigators in reported mean chiasma frequencies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brown W. M., Law P., Smith P. G. Sex chromosome aneuploidy and parental age. Ann Hum Genet. 1969 Jul;33(1):1–14. doi: 10.1111/j.1469-1809.1969.tb01623.x. [DOI] [PubMed] [Google Scholar]
  2. Datta M. Study of meiosis in the chimpanzee, Pan troglodytes troglodytes (Blumenbach 1779). Cytologia (Tokyo) 1972 Jun;37(2):207–216. doi: 10.1508/cytologia.37.207. [DOI] [PubMed] [Google Scholar]
  3. FORD C. E., HAMERTON J. L. The chromosomes of man. Nature. 1956 Nov 10;178(4541):1020–1023. doi: 10.1038/1781020a0. [DOI] [PubMed] [Google Scholar]
  4. Fu T. K., Sears E. R. The Relationship between Chiasmata and Crossing over in TRITICUM AESTIVUM. Genetics. 1973 Oct;75(2):231–246. doi: 10.1093/genetics/75.2.231. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Hamerton J. L., Cock P. J. Proceedings: Report of the Committee on the Genetic Constitution of Chromosome 1. Cytogenet Cell Genet. 1974;13(1):13–20. doi: 10.1159/000130226. [DOI] [PubMed] [Google Scholar]
  6. Henderson S. A., Edwards R. G. Chiasma frequency and maternal age in mammals. Nature. 1968 Apr 6;218(5136):22–28. doi: 10.1038/218022a0. [DOI] [PubMed] [Google Scholar]
  7. Lazyuk G. I., Kravtosova G. I., Kulazhenko V. P., Usova YuI, Usoev S. S. Analysis of 137 cases of the trisomy-D syndrome. Sov Genet. 1974 Jan 15;7(10):1338–1349. [PubMed] [Google Scholar]
  8. Luciani J. M. Les chromosomes méiotiques de l'homme. I. La méiose normale. Ann Genet. 1970 Jun;13(2):101–111. [PubMed] [Google Scholar]
  9. Luciani J. M. Les chromosomes méiotiques de l'homme. II. Le nucléole. Les chiasmas. 3. La stérilité masculine. Ann Genet. 1970 Sep;13(3):169–182. [PubMed] [Google Scholar]
  10. Luthardt F. W., Palmer C. G., Yu P. Chiasma and univalent frequencies in aging female mice. Cytogenet Cell Genet. 1973;12(1):68–79. doi: 10.1159/000130440. [DOI] [PubMed] [Google Scholar]
  11. McDermott A. The frequency and distribution of chiasmata in man. Ann Hum Genet. 1973 Jul;37(1):13–20. doi: 10.1111/j.1469-1809.1973.tb01810.x. [DOI] [PubMed] [Google Scholar]
  12. Page B. M. Identification of chromosome 9 in human male meiosis. Cytogenet Cell Genet. 1973;12(4):254–263. doi: 10.1159/000130461. [DOI] [PubMed] [Google Scholar]
  13. Polani P. E. Autosomal imbalance and its syndromes, excluding down's. Br Med Bull. 1969 Jan;25(1):81–93. doi: 10.1093/oxfordjournals.bmb.a070675. [DOI] [PubMed] [Google Scholar]
  14. Skakkebaek N. E., Bryant J. I., Philip J. Studies on meiotic chromosomes in infertile men and controls with normak karyotypes. J Reprod Fertil. 1973 Oct;35(1):23–36. doi: 10.1530/jrf.0.0350023. [DOI] [PubMed] [Google Scholar]
  15. Skakkebaek N. E., Heller C. G. Quantification of human seminiferous epithelium. I. Histological studies in twenty-one fertile men with normal chromosome complements. J Reprod Fertil. 1973 Mar;32(3):379–389. doi: 10.1530/jrf.0.0320379. [DOI] [PubMed] [Google Scholar]
  16. Taylor A. I. Autosomal trisomy syndromes: a detailed study of 27 cases of Edwards' syndrome and 27 cases of Patau's syndrome. J Med Genet. 1968 Sep;5(3):227–252. doi: 10.1136/jmg.5.3.227. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Tulloch W. S., Newsam J. E. Studies on human meiotic chromosomes from testicular tissue. Lancet. 1966 Mar 26;1(7439):679–682. doi: 10.1016/s0140-6736(66)91627-8. [DOI] [PubMed] [Google Scholar]
  18. Weitkamp L. R., Van Rood J. J., Thorsby E., Bias W., Fotino M., Lawler S. D., Dausset J., Mayr W. R., Bodmer J., Ward F. E. The relation of parental sex and age to recombination in the HL-A system. Hum Hered. 1973;23(3):197–205. doi: 10.1159/000152574. [DOI] [PubMed] [Google Scholar]
  19. Yuncken C. Meiosis in the human female. Cytogenetics. 1968;7(3):234–238. doi: 10.1159/000129986. [DOI] [PubMed] [Google Scholar]

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