Photodynamic treatment of pooled coumarin plasma for external quality assessment of the prothrombin time.

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Figure 6 International normalised ratio (INR) of pooled coumarin plasma determined with bovine thromboplastin (Thrombotest) after treatment with 1 µM methylene blue and incandescent light (700 W/m²). Before illumination, either air (open circle) or nitrogen (open square) was bubbled through the plasma, or no additional treatment was given (cross).