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Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 2002 Nov;87(5):376–379. doi: 10.1136/adc.87.5.376

A parent completed questionnaire to describe the patterns of wheezing and other respiratory symptoms in infants and preschool children

C Powell 1, P McNamara 1, A Solis 1, N Shaw 1
PMCID: PMC1763091  PMID: 12390904

Abstract

Aim: To develop a standardised and validated respiratory symptom questionnaire for use in epidemiological or follow up studies in infants and preschool children.

Methodology: After initial design and development, the questionnaire was administered to two cohorts of subjects, one recruited from a respiratory clinic and the other from a postnatal ward. The two cohorts then repeated the questionnaire, two weeks apart. The qualities of the questionnaire were assessed.

Results: Response rate to the initial questionnaire was 100% for the clinic based cohort and 64% for postnatally recruited families (total number of subjects 114). Questions showed good to moderate short term reliability (weighted kappa scores 0.47–0.7; average correct classification rates 0.74–0.91). Four domain concept scores showed excellent internal consistency (Cronbach alpha scores 0.87–0.95). Using principal component factor analysis, four new domains were devised showing acceptable construct validity and internal consistency. Criterion validity was assessed using a respiratory physician based diagnosis of asthma (RPBDA) as the gold standard for comparison. All eight scales in the questionnaire could significantly distinguish between infants with RPBDA and well or mildly symptomatic subjects.

Conclusion: We have developed a practical, acceptable questionnaire with eight concept domains for use in infants and preschool children. The questionnaire has strong construct validity and internal consistency with good short term reliability of questions. More detailed study of criterion validity and the responsiveness of the questionnaire is required using a larger population and including children with the different phenotypes of wheezy illness.

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Selected References

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  1. Asher M. I., Keil U., Anderson H. R., Beasley R., Crane J., Martinez F., Mitchell E. A., Pearce N., Sibbald B., Stewart A. W. International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J. 1995 Mar;8(3):483–491. doi: 10.1183/09031936.95.08030483. [DOI] [PubMed] [Google Scholar]
  2. Chinn S., Burney P. G. On measuring repeatability of data from self-administered questionnaires. Int J Epidemiol. 1987 Mar;16(1):121–127. doi: 10.1093/ije/16.1.121. [DOI] [PubMed] [Google Scholar]
  3. Clifford R. D., Radford M., Howell J. B., Holgate S. T. Prevalence of respiratory symptoms among 7 and 11 year old schoolchildren and association with asthma. Arch Dis Child. 1989 Aug;64(8):1118–1125. doi: 10.1136/adc.64.8.1118. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Clough J. B., Williams J. D., Holgate S. T. Profile of bronchial responsiveness in children with respiratory symptoms. Arch Dis Child. 1992 May;67(5):574–579. doi: 10.1136/adc.67.5.574. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Elphick H. E., Sherlock P., Foxall G., Simpson E. J., Shiell N. A., Primhak R. A., Everard M. L. Survey of respiratory sounds in infants. Arch Dis Child. 2001 Jan;84(1):35–39. doi: 10.1136/adc.84.1.35. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Faniran A. O., Peat J. K., Woolcock A. J. Measuring persistent cough in children in epidemiological studies: development of a questionnaire and assessment of prevalence in two countries. Chest. 1999 Feb;115(2):434–439. doi: 10.1378/chest.115.2.434. [DOI] [PubMed] [Google Scholar]
  7. Juniper E. F., Buist A. S., Cox F. M., Ferrie P. J., King D. R. Validation of a standardized version of the Asthma Quality of Life Questionnaire. Chest. 1999 May;115(5):1265–1270. doi: 10.1378/chest.115.5.1265. [DOI] [PubMed] [Google Scholar]
  8. Le Souëf P. N. Validity of methods used to test airway responsiveness in children. Lancet. 1992 May 23;339(8804):1282–1284. doi: 10.1016/0140-6736(92)91602-5. [DOI] [PubMed] [Google Scholar]
  9. Luyt D. K., Burton P. R., Simpson H. Epidemiological study of wheeze, doctor diagnosed asthma, and cough in preschool children in Leicestershire. BMJ. 1993 May 22;306(6889):1386–1390. doi: 10.1136/bmj.306.6889.1386. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Luyt D. K., Burton P., Brooke A. M., Simpson H. Wheeze in preschool children and its relation with doctor diagnosed asthma. Arch Dis Child. 1994 Jul;71(1):24–30. doi: 10.1136/adc.71.1.24. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Martinez F. D., Wright A. L., Taussig L. M., Holberg C. J., Halonen M., Morgan W. J. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med. 1995 Jan 19;332(3):133–138. doi: 10.1056/NEJM199501193320301. [DOI] [PubMed] [Google Scholar]
  12. Ninan T. K., Russell G. Respiratory symptoms and atopy in Aberdeen schoolchildren: evidence from two surveys 25 years apart. BMJ. 1992 Apr 4;304(6831):873–875. doi: 10.1136/bmj.304.6831.873. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Primhak R. A., Powell C. V. E. AHR in asthma. Thorax. 2002 Feb;57(2):186–186. doi: 10.1136/thorax.57.2.186-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Robertson C. F., Heycock E., Bishop J., Nolan T., Olinsky A., Phelan P. D. Prevalence of asthma in Melbourne schoolchildren: changes over 26 years. BMJ. 1991 May 11;302(6785):1116–1118. doi: 10.1136/bmj.302.6785.1116. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Rosier M. J., Bishop J., Nolan T., Robertson C. F., Carlin J. B., Phelan P. D. Measurement of functional severity of asthma in children. Am J Respir Crit Care Med. 1994 Jun;149(6):1434–1441. doi: 10.1164/ajrccm.149.6.8004295. [DOI] [PubMed] [Google Scholar]
  16. Silverman M., Wilson N. Asthma--time for a change of name? Arch Dis Child. 1997 Jul;77(1):62–65. doi: 10.1136/adc.77.1.62. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Silverman M., Wilson N. Wheezing phenotypes in childhood. Thorax. 1997 Nov;52(11):936–937. doi: 10.1136/thx.52.11.936. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Stein R. T., Holberg C. J., Morgan W. J., Wright A. L., Lombardi E., Taussig L., Martinez F. D. Peak flow variability, methacholine responsiveness and atopy as markers for detecting different wheezing phenotypes in childhood. Thorax. 1997 Nov;52(11):946–952. doi: 10.1136/thx.52.11.946. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Usherwood T. P., Scrimgeour A., Barber J. H. Questionnaire to measure perceived symptoms and disability in asthma. Arch Dis Child. 1990 Jul;65(7):779–781. doi: 10.1136/adc.65.7.779. [DOI] [PMC free article] [PubMed] [Google Scholar]

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