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. 2003 Jul;88(7):601–607. doi: 10.1136/adc.88.7.601

Pathophysiology of meningococcal meningitis and septicaemia

N Pathan 1, S Faust 1, M Levin 1
PMCID: PMC1763171  PMID: 12818907

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Figure 1.

Figure 1

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The inflammatory cascade in meningococcal septicaemia.

Figure 2.

Figure 2

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(A) The inflammatory, coagulation, and fibrinolytic pathways are linked at many levels, leading to organ failure and eventually death. (B) The coagulation and fibrinolytic pathways rely on the function of endothelial proteins and protein complexes. Dysfunctional regulatory mechanisms in meningococcal disease include endothelial (protein C pathway) and plasma (TFPI, antithrombin, PAI) factors.

Figure 3.

Figure 3

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Factors involved in intravascular thrombosis and purpura fulminans.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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