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. 1985 Jul;28(1):141–143. doi: 10.1128/aac.28.1.141

Tetracycline-resistant Mycoplasma hominis strains contain streptococcal tetM sequences.

M C Roberts, L A Koutsky, K K Holmes, D J LeBlanc, G E Kenny
PMCID: PMC176326  PMID: 2994555

Abstract

Clinical isolates of Mycoplasma hominis resistant to high levels of tetracycline contained DNA sequences homologous to the streptococcal tetracycline determinant, tetM. In contrast, none of the susceptible M. hominis isolates tested carried this determinant. This is the first description of tetM in an unrelated genus and suggests the spread of tetM from Streptococcus spp. to Mycoplasma spp.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burdett V. Identification of tetracycline-resistant R-plasmids in Streptococcus agalactiae (group B). Antimicrob Agents Chemother. 1980 Nov;18(5):753–760. doi: 10.1128/aac.18.5.753. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Burdett V., Inamine J., Rajagopalan S. Heterogeneity of tetracycline resistance determinants in Streptococcus. J Bacteriol. 1982 Mar;149(3):995–1004. doi: 10.1128/jb.149.3.995-1004.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CLYDE W. A., Jr MYCOPLASMA SPECIES IDENTIFICATION BASED UPON GROWTH INHIBITION BY SPECIFIC ANTISERA. J Immunol. 1964 Jun;92:958–965. [PubMed] [Google Scholar]
  4. Chang A. C., Cohen S. N. Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. J Bacteriol. 1978 Jun;134(3):1141–1156. doi: 10.1128/jb.134.3.1141-1156.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Franke A. E., Clewell D. B. Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of "conjugal" transfer in the absence of a conjugative plasmid. J Bacteriol. 1981 Jan;145(1):494–502. doi: 10.1128/jb.145.1.494-502.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Furness G., Cerone A. M. Preparation of competent single-cell suspensions of Mycoplasma hominis tets and Mycoplasma salivarium tets for genetic transformation to tetracycline resistance by DNA extracted from Mycoplamsa hominis tetr. J Infect Dis. 1979 Apr;139(4):444–451. doi: 10.1093/infdis/139.4.444. [DOI] [PubMed] [Google Scholar]
  7. Hartley D. L., Jones K. R., Tobian J. A., LeBlanc D. J., Macrina F. L. Disseminated tetracycline resistance in oral streptococci: implication of a conjugative transposon. Infect Immun. 1984 Jul;45(1):13–17. doi: 10.1128/iai.45.1.13-17.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Hjelm E., Jonsell G., Linglöf T., Mårdh P. A., Møller B., Sedin G. Meningitis in a newborn infant caused by Mycoplasma hominis. Acta Paediatr Scand. 1980 May;69(3):415–418. doi: 10.1111/j.1651-2227.1980.tb07103.x. [DOI] [PubMed] [Google Scholar]
  9. Jagielski M. Wrazliwoś Mycoplasma hominis na wybrane antybiotyki. Med Dosw Mikrobiol. 1979;31(4):225–237. [PubMed] [Google Scholar]
  10. Kenny G. E. Heat-lability and organic solvent-solubility of mycoplasma antigens. Ann N Y Acad Sci. 1967 Jul 28;143(1):676–681. doi: 10.1111/j.1749-6632.1967.tb27713.x. [DOI] [PubMed] [Google Scholar]
  11. Koutsky L. A., Stamm W. E., Brunham R. C., Stevens C. E., Cole B., Hale J., Davick P., Holmes K. K. Persistence of Mycoplasma hominis after therapy: importance of tetracycline resistance and of coexisting vaginal flora. Sex Transm Dis. 1983 Oct-Dec;10(4 Suppl):374–381. [PubMed] [Google Scholar]
  12. Mendez B., Tachibana C., Levy S. B. Heterogeneity of tetracycline resistance determinants. Plasmid. 1980 Mar;3(2):99–108. doi: 10.1016/0147-619x(80)90101-8. [DOI] [PubMed] [Google Scholar]
  13. Roberts M. C., Hillier S. L., Schoenknecht F. D., Holmes K. K. Nitrocellulose filter blots for species identification of Mobiluncus curtisii and Mobiluncus mulieris. J Clin Microbiol. 1984 Oct;20(4):826–827. doi: 10.1128/jcm.20.4.826-827.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Southern E. M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975 Nov 5;98(3):503–517. doi: 10.1016/s0022-2836(75)80083-0. [DOI] [PubMed] [Google Scholar]
  15. Woese C. R., Maniloff J., Zablen L. B. Phylogenetic analysis of the mycoplasmas. Proc Natl Acad Sci U S A. 1980 Jan;77(1):494–498. doi: 10.1073/pnas.77.1.494. [DOI] [PMC free article] [PubMed] [Google Scholar]

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