Skip to main content
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 2004 May;75(5):700–705. doi: 10.1136/jnnp.2003.021055

The seven minute screen: a neurocognitive screening test highly sensitive to various types of dementia

E Meulen 1, B Schmand 1, J P van Campen 1, S J de Koning 1, R Ponds 1, P Scheltens 1, F Verhey 1
PMCID: PMC1763549  PMID: 15090563

Abstract

Background: The seven minute screen (7MS) is a compilation of the temporal orientation test, enhanced cued recall, clock drawing, and verbal fluency. It has been shown to be useful for detecting Alzheimer's disease in a population of patients with memory complaints.

Objective: To assess the predictive validity of the 7MS for various types of dementia, and the influence of depression and other psychiatric conditions on 7MS scores.

Setting: Multicentre: secondary referral sites across the Netherlands.

Subjects: 542 patients with various types of dementia or depression, together with 45 healthy controls.

Results: Alzheimer's disease was diagnosed in 177 patients, other types of dementia in 164. The sensitivity of the 7MS for Alzheimer's disease was 92.9% with a specificity of 93.5%. For other types of dementia the sensitivity was 89.4% and the specificity 93.5%. Cognitive abnormalities were found in 71% of the patients with depression (n = 31). The mean (SD) duration of administration of the 7MS was 12.4 (4.6) minutes, range 8 to 22, depending on dementia severity.

Conclusions: The 7MS is a useful screening tool for discriminating patients with dementia from cognitively intact patients. This not only applies to Alzheimer's disease but also to other types of dementia. Specificity with respect to depression was lower for the 7MS than for the MMSE.

Full Text

The Full Text of this article is available as a PDF (396.4 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Berger A. K., Fratiglioni L., Forsell Y., Winblad B., Bäckman L. The occurrence of depressive symptoms in the preclinical phase of AD: a population-based study. Neurology. 1999 Dec 10;53(9):1998–2002. doi: 10.1212/wnl.53.9.1998. [DOI] [PubMed] [Google Scholar]
  2. Butters M. A., Becker J. T., Nebes R. D., Zmuda M. D., Mulsant B. H., Pollock B. G., Reynolds C. F., 3rd Changes in cognitive functioning following treatment of late-life depression. Am J Psychiatry. 2000 Dec;157(12):1949–1954. doi: 10.1176/appi.ajp.157.12.1949. [DOI] [PubMed] [Google Scholar]
  3. Cummings J. L., Benson D. F. Subcortical dementia. Review of an emerging concept. Arch Neurol. 1984 Aug;41(8):874–879. doi: 10.1001/archneur.1984.04050190080019. [DOI] [PubMed] [Google Scholar]
  4. Folstein M. F., Folstein S. E., McHugh P. R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975 Nov;12(3):189–198. doi: 10.1016/0022-3956(75)90026-6. [DOI] [PubMed] [Google Scholar]
  5. Grober E., Buschke H., Crystal H., Bang S., Dresner R. Screening for dementia by memory testing. Neurology. 1988 Jun;38(6):900–903. doi: 10.1212/wnl.38.6.900. [DOI] [PubMed] [Google Scholar]
  6. Heun R., Papassotiropoulos A., Jennssen F. The validity of psychometric instruments for detection of dementia in the elderly general population. Int J Geriatr Psychiatry. 1998 Jun;13(6):368–380. doi: 10.1002/(sici)1099-1166(199806)13:6<368::aid-gps775>3.0.co;2-9. [DOI] [PubMed] [Google Scholar]
  7. Hébert R., Lindsay J., Verreault R., Rockwood K., Hill G., Dubois M. F. Vascular dementia : incidence and risk factors in the Canadian study of health and aging. Stroke. 2000 Jul;31(7):1487–1493. doi: 10.1161/01.str.31.7.1487. [DOI] [PubMed] [Google Scholar]
  8. Lindeboom J., Schmand B., Tulner L., Walstra G., Jonker C. Visual association test to detect early dementia of the Alzheimer type. J Neurol Neurosurg Psychiatry. 2002 Aug;73(2):126–133. doi: 10.1136/jnnp.73.2.126. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Lyketsos Constantine G., Lopez Oscar, Jones Beverly, Fitzpatrick Annette L., Breitner John, DeKosky Steven. Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA. 2002 Sep 25;288(12):1475–1483. doi: 10.1001/jama.288.12.1475. [DOI] [PubMed] [Google Scholar]
  10. McKeith I. G., Galasko D., Kosaka K., Perry E. K., Dickson D. W., Hansen L. A., Salmon D. P., Lowe J., Mirra S. S., Byrne E. J. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology. 1996 Nov;47(5):1113–1124. doi: 10.1212/wnl.47.5.1113. [DOI] [PubMed] [Google Scholar]
  11. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E. M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984 Jul;34(7):939–944. doi: 10.1212/wnl.34.7.939. [DOI] [PubMed] [Google Scholar]
  12. Neary D., Snowden J. S., Gustafson L., Passant U., Stuss D., Black S., Freedman M., Kertesz A., Robert P. H., Albert M. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology. 1998 Dec;51(6):1546–1554. doi: 10.1212/wnl.51.6.1546. [DOI] [PubMed] [Google Scholar]
  13. Petersen R. C., Doody R., Kurz A., Mohs R. C., Morris J. C., Rabins P. V., Ritchie K., Rossor M., Thal L., Winblad B. Current concepts in mild cognitive impairment. Arch Neurol. 2001 Dec;58(12):1985–1992. doi: 10.1001/archneur.58.12.1985. [DOI] [PubMed] [Google Scholar]
  14. Petersen R. C., Smith G. E., Waring S. C., Ivnik R. J., Tangalos E. G., Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999 Mar;56(3):303–308. doi: 10.1001/archneur.56.3.303. [DOI] [PubMed] [Google Scholar]
  15. Powlishta K. K., Von Dras D. D., Stanford A., Carr D. B., Tsering C., Miller J. P., Morris J. C. The clock drawing test is a poor screen for very mild dementia. Neurology. 2002 Sep 24;59(6):898–903. doi: 10.1212/wnl.59.6.898. [DOI] [PubMed] [Google Scholar]
  16. Shulman K. I. Clock-drawing: is it the ideal cognitive screening test? Int J Geriatr Psychiatry. 2000 Jun;15(6):548–561. doi: 10.1002/1099-1166(200006)15:6<548::aid-gps242>3.0.co;2-u. [DOI] [PubMed] [Google Scholar]
  17. Solomon P. R., Brush M., Calvo V., Adams F., DeVeaux R. D., Pendlebury W. W., Sullivan D. M. Identifying dementia in the primary care practice. Int Psychogeriatr. 2000 Dec;12(4):483–493. doi: 10.1017/s1041610200006608. [DOI] [PubMed] [Google Scholar]
  18. Solomon P. R., Hirschoff A., Kelly B., Relin M., Brush M., DeVeaux R. D., Pendlebury W. W. A 7 minute neurocognitive screening battery highly sensitive to Alzheimer's disease. Arch Neurol. 1998 Mar;55(3):349–355. doi: 10.1001/archneur.55.3.349. [DOI] [PubMed] [Google Scholar]
  19. Tombaugh T. N., McIntyre N. J. The mini-mental state examination: a comprehensive review. J Am Geriatr Soc. 1992 Sep;40(9):922–935. doi: 10.1111/j.1532-5415.1992.tb01992.x. [DOI] [PubMed] [Google Scholar]
  20. Tsolaki Magda, Iakovidou Vasso, Papadopoulou Efi, Aminta Marianna, Nakopoulou Evagelia, Pantazi Theoharis, Kazis Aristides. Greek validation of the seven-minute screening battery for Alzheimer's disease in the elderly. Am J Alzheimers Dis Other Demen. 2002 May-Jun;17(3):139–148. doi: 10.1177/153331750201700311. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Wilson Robert S., Barnes L. L., Mendes de Leon C. F., Aggarwal N. T., Schneider J. S., Bach J., Pilat J., Beckett L. A., Arnold S. E., Evans D. A. Depressive symptoms, cognitive decline, and risk of AD in older persons. Neurology. 2002 Aug 13;59(3):364–370. doi: 10.1212/wnl.59.3.364. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES