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. 2002 Dec;59(12):816–823. doi: 10.1136/oem.59.12.816

Cross sectional study on lung function of coke oven workers: a lung function surveillance system from 1978 to 1990

J Wu 1, I Kreis 1, D Griffiths 1, C Darling 1
PMCID: PMC1763602  PMID: 12468747

Abstract

Aims: To determine the association between lung function of coke oven workers and exposure to coke oven emissions.

Methods: Lung function data and detailed work histories for workers in recovery coke ovens of a steelworks were extracted from a lung function surveillance system. Multiple regressions were employed to determine significant predictors for lung function indices. The first sets of lung function tests for 613 new starters were pooled to assess the selection bias. The last sets of lung function tests for 834 subjects with one or more year of coke oven history were pooled to assess determinants of lung function.

Results: Selection bias associated with the recruitment process was not observed among the exposure groups. For subjects with a history of one or more years of coke oven work, each year of working in the most exposed "operation" position was associated with reductions in FEV1 of around 9 ml (p = 0.006, 95% CI: 3 ml to 16 ml) and in FVC of around 12 ml (p = 0.002, 95% CI: 4 ml to 19 ml). Negative effects of smoking on lung function were also observed.

Conclusions: Exposure to coke oven emissions was found to be associated with lower FEV1 and FVC. Effects of work exposure on lung function are similar to those found in other studies.

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Selected References

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  1. Ashley F., Kannel W. B., Sorlie P. D., Masson R. Pulmonary function: relation to aging, cigarette habit, and mortality. Ann Intern Med. 1975 Jun;82(6):739–745. doi: 10.7326/0003-4819-82-6-739. [DOI] [PubMed] [Google Scholar]
  2. Bande J., Clément J., Van de Woestijne K. P. The influence of smoking habits and body weight on vital capacity and FEV1 in male Air Force personnel: a longitudinal and cross-sectional analysis. Am Rev Respir Dis. 1980 Nov;122(5):781–790. doi: 10.1164/arrd.1980.122.5.781. [DOI] [PubMed] [Google Scholar]
  3. Bates D. V., Pham Q. T., Chau N., Pivoteau C., Dechoux J., Sadoul P. A longitudinal study of pulmonary function in coal miners in Lorraine, France. Am J Ind Med. 1985;8(1):21–32. doi: 10.1002/ajim.4700080104. [DOI] [PubMed] [Google Scholar]
  4. Burton P., Gurrin L., Sly P. Extending the simple linear regression model to account for correlated responses: an introduction to generalized estimating equations and multi-level mixed modelling. Stat Med. 1998 Jun 15;17(11):1261–1291. doi: 10.1002/(sici)1097-0258(19980615)17:11<1261::aid-sim846>3.0.co;2-z. [DOI] [PubMed] [Google Scholar]
  5. Chau N., Bertrand J. P., Guenzi M., Mayer L., Téculescu D., Mur J. M., Patris A., Moulin J. J., Pham Q. T. Lung function in retired coke oven plant workers. Br J Ind Med. 1992 May;49(5):316–325. doi: 10.1136/oem.49.5.316. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Cole T. J. Height standardization of ventilatory function. Proc R Soc Med. 1977 Mar;70(3):165–166. [PMC free article] [PubMed] [Google Scholar]
  7. Corhay J. L., Bury T., Louis R., Delavignette J. P., Kayembe J. M., Weber G., Albert A., Radermecker M. F. Bronchial responsiveness in active steelworkers. Eur Respir J. 1998 Feb;11(2):272–277. doi: 10.1183/09031936.98.11020272. [DOI] [PubMed] [Google Scholar]
  8. Crapo R. O., Morris A. H., Gardner R. M. Reference spirometric values using techniques and equipment that meet ATS recommendations. Am Rev Respir Dis. 1981 Jun;123(6):659–664. doi: 10.1164/arrd.1981.123.6.659. [DOI] [PubMed] [Google Scholar]
  9. Dancy T. E. Control of coke oven emissions. J Occup Med. 1971 Feb;13(2):75–82. doi: 10.1097/00043764-197102000-00003. [DOI] [PubMed] [Google Scholar]
  10. Davies G. M., Hodkinson A., DiVetta P. Measurement and analysis of occupational exposures to coke oven emissions. Ann Occup Hyg. 1986;30(1):51–62. doi: 10.1093/annhyg/30.1.51. [DOI] [PubMed] [Google Scholar]
  11. Ericsson P., Irnell L. Spirometric studies of ventilatory capacity in elderly people. Acta Med Scand. 1969 Mar;185(3):179–184. doi: 10.1111/j.0954-6820.1969.tb07317.x. [DOI] [PubMed] [Google Scholar]
  12. Gamble J., Jones W., Hudak J. An epidemiological study of salt miners in diesel and nondiesel mines. Am J Ind Med. 1983;4(3):435–458. doi: 10.1002/ajim.4700040305. [DOI] [PubMed] [Google Scholar]
  13. Gibson J., Gallagher H., Johansen A., Webster I. Lung function in an Australian population: 1. Spirometric standards for non-smoking adults. Med J Aust. 1979 Apr 7;1(7):292–295. doi: 10.5694/j.1326-5377.1979.tb112111.x. [DOI] [PubMed] [Google Scholar]
  14. Gore C. J., Crockett A. J., Pederson D. G., Booth M. L., Bauman A., Owen N. Spirometric standards for healthy adult lifetime nonsmokers in Australia. Eur Respir J. 1995 May;8(5):773–782. [PubMed] [Google Scholar]
  15. Hankinson J. L. Pulmonary function testing in the screening of workers: guidelines for instrumentation, performance, and interpretation. J Occup Med. 1986 Oct;28(10):1081–1092. doi: 10.1097/00043764-198610000-00032. [DOI] [PubMed] [Google Scholar]
  16. Hoek G., Brunekreef B. Time trends in repeated spirometry in children. Eur Respir J. 1992 May;5(5):553–559. [PubMed] [Google Scholar]
  17. Huhti E. Ventilatory function in healthy non-smokers and smokers. Scand J Respir Dis. 1967;48(2):149–155. [PubMed] [Google Scholar]
  18. Jörgensen H. S., Kolmodin-Hedman B., Stjernberg N. Follow-up study of pulmonary function and respiratory tract symptoms in workers in a Swedish iron ore mine. J Occup Med. 1988 Dec;30(12):953–958. doi: 10.1097/00043764-198812000-00014. [DOI] [PubMed] [Google Scholar]
  19. Lloyd J. W. Long-term mortality study of steelworkers. V. Respiratory cancer in coke plant workers. J Occup Med. 1971 Feb;13(2):53–68. [PubMed] [Google Scholar]
  20. Love R. G., Miller B. G. Longitudinal study of lung function in coal-miners. Thorax. 1982 Mar;37(3):193–197. doi: 10.1136/thx.37.3.193. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Lowe C. R., Pelmear P. L., Campbell H., Hitchens R. A., Khosla T., King T. C. Bronchitis in two integrated steel works. I. Ventilatory capacity, age, and physique of non-bronchitic men. Br J Prev Soc Med. 1968 Jan;22(1):1–11. doi: 10.1136/jech.22.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Madison R., Afifi A. A., Mittman C. Respiratory impairment in coke oven workers: relationship to work exposure and bronchial inflammation detected by sputum cytology. J Chronic Dis. 1984;37(3):167–176. doi: 10.1016/0021-9681(84)90144-9. [DOI] [PubMed] [Google Scholar]
  23. Mancuso T. F. Lung cancer among black migrants. Interaction of host and occupational environment factors. J Occup Med. 1977 Aug;19(8):531–532. [PubMed] [Google Scholar]
  24. Morris J. F., Koski A., Johnson L. C. Spirometric standards for healthy nonsmoking adults. Am Rev Respir Dis. 1971 Jan;103(1):57–67. doi: 10.1164/arrd.1971.103.1.57. [DOI] [PubMed] [Google Scholar]
  25. Quanjer P. H., Tammeling G. J., Cotes J. E., Pedersen O. F., Peslin R., Yernault J. C. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl. 1993 Mar;16:5–40. [PubMed] [Google Scholar]
  26. Redmond C. K., Ciocco A., Lloyd J. W., Rush H. W. Long-term mortality study of steelworkers. VI. Mortality from malignant neoplasms among coke oven workers. J Occup Med. 1972 Aug;14(8):621–629. [PubMed] [Google Scholar]
  27. Redmond C. K., Strobino B. R., Cypess R. H. Cancer experience among coke by-product workers. Ann N Y Acad Sci. 1976;271:102–115. doi: 10.1111/j.1749-6632.1976.tb23099.x. [DOI] [PubMed] [Google Scholar]
  28. Schoenberg J. B., Beck G. J., Bouhuys A. Growth and decay of pulmonary function in healthy blacks and whites. Respir Physiol. 1978 Jun;33(3):367–393. doi: 10.1016/0034-5687(78)90063-4. [DOI] [PubMed] [Google Scholar]
  29. Smith W. M. Evaluation of coke oven emissions. J Occup Med. 1971 Feb;13(2):69–74. doi: 10.1097/00043764-197102000-00002. [DOI] [PubMed] [Google Scholar]
  30. Soutar C. A., Hurley J. F. Relation between dust exposure and lung function in miners and ex-miners. Br J Ind Med. 1986 May;43(5):307–320. doi: 10.1136/oem.43.5.307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Swaen G. M., Slangen J. J., Volovics A., Hayes R. B., Scheffers T., Sturmans F. Mortality of coke plant workers in The Netherlands. Br J Ind Med. 1991 Feb;48(2):130–135. doi: 10.1136/oem.48.2.130. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Vollmer W. M., Johnson L. R., McCamant L. E., Buist A. S. Longitudinal versus cross-sectional estimation of lung function decline--further insights. Stat Med. 1988 Jun;7(6):685–696. doi: 10.1002/sim.4780070607. [DOI] [PubMed] [Google Scholar]
  33. Vollmer W. M., Johnson L. R., McCamant L. E., Buist A. S. Methodologic issues in the analysis of lung function data. J Chronic Dis. 1987;40(11):1013–1023. doi: 10.1016/0021-9681(87)90115-9. [DOI] [PubMed] [Google Scholar]
  34. Walker D. D., Archibald R. M., Attfield M. D. Bronchitis in men employed in the coke industry. Br J Ind Med. 1971 Oct;28(4):358–363. doi: 10.1136/oem.28.4.358. [DOI] [PMC free article] [PubMed] [Google Scholar]

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