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. 1986 Feb;29(2):284–288. doi: 10.1128/aac.29.2.284

New agents active against African swine fever virus.

A Sola, S Rodríguez, C Gil-Fernández, B Alarcón, M E González, L Carrasco
PMCID: PMC176392  PMID: 3717934

Abstract

Actinobolin, atropine, carrageenan, megalomycin C, suramin, and tetracenomycin C were tested for their activity against African swine fever virus replication. Both viral inhibitory potency and cytotoxicity were investigated. Megalomycin C, suramin, atropine, and carrageenan exhibited significant activity. Megalomycin C was the most active of the four agents with respect to the concentration of compound that blocked the formation of infectious virus by 50%. Suramin was the next most active agent in this respect, but because of its lower cytotoxicity, it had the most favorable therapeutic index.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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