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. 1986 Feb;29(2):342–343. doi: 10.1128/aac.29.2.342

Enhanced toxicity of copper for Streptococcus mutans under anaerobic conditions.

S L Evans, C Tolbert, J E Arceneaux, B R Byers
PMCID: PMC176406  PMID: 3087278

Abstract

Copper inhibition of 11 strains (serotypes a through g) of Streptococcus mutans was increased by anaerobic incubation. Anaerobic toxicity was reversed by cuprous, but not by cupric, chelators. Susceptibility to aerobic copper inhibition was related to serotype; serotypes c, e, and f (biotype I) were most sensitive.

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Selected References

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  1. Afseth J., Amsbaugh S. M., Monell-Torrens E., Bowen W. H., Rölla G., Brunelle J., Li S., Dahl E. Effect of topical application of copper in combination with fluoride in drinking water on experimental caries in rats. Caries Res. 1984;18(2):134–140. doi: 10.1159/000260761. [DOI] [PubMed] [Google Scholar]
  2. Aranha H., Strachan R. C., Arceneaux J. E., Byers B. R. Effect of trace metals on growth of Streptococcus mutans in a teflon chemostat. Infect Immun. 1982 Feb;35(2):456–460. doi: 10.1128/iai.35.2.456-460.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bowen W. H. The trace element requirements of cariogenic and non-cariogenic streptococci. Arch Oral Biol. 1968 Jun;13(6):713–714. doi: 10.1016/0003-9969(68)90151-9. [DOI] [PubMed] [Google Scholar]
  4. Cole J. A. A biochemical approach to the control of dental caries. Biochem Soc Trans. 1977;5(4):1232–1239. doi: 10.1042/bst0051232. [DOI] [PubMed] [Google Scholar]
  5. Fitzgerald D. B., Fitzgerald R. J., Adams B. O., Morhart R. E. Prevalence, distribution of serotypes, and cariogenic potential in hamsters of mutans streptococci from elderly individuals. Infect Immun. 1983 Aug;41(2):691–697. doi: 10.1128/iai.41.2.691-697.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Martin M. E., Strachan R. C., Aranha H., Evans S. L., Salin M. L., Welch B., Arceneaux J. E., Byers B. R. Oxygen toxicity in Streptococcus mutans: manganese, iron, and superoxide dismutase. J Bacteriol. 1984 Aug;159(2):745–749. doi: 10.1128/jb.159.2.745-749.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Oppermann R. V., Johansen J. R. Effect of fluoride and non-fluoride salts of copper, silver and tin on the acidogenicity of dental plaque in vivo. Scand J Dent Res. 1980 Dec;88(6):476–480. doi: 10.1111/j.1600-0722.1980.tb01257.x. [DOI] [PubMed] [Google Scholar]
  8. Oppermann R. V., Rölla G. Effect of some polyvalent cations on the acidogenicity of dental plaque in vivo. Caries Res. 1980;14(6):422–427. doi: 10.1159/000260485. [DOI] [PubMed] [Google Scholar]
  9. Tenovuo J., Valtakoski J. The correlation between salivary peroxidase activity, salivary flow rate, and the oxidation-reduction potentials of human saliva and dental plaque suspensions. Acta Odontol Scand. 1976;34(3):169–176. doi: 10.3109/00016357609002565. [DOI] [PubMed] [Google Scholar]
  10. Thomas E. L., Pera K. A. Oxygen metabolism of Streptococcus mutans: uptake of oxygen and release of superoxide and hydrogen peroxide. J Bacteriol. 1983 Jun;154(3):1236–1244. doi: 10.1128/jb.154.3.1236-1244.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Waerhaug M., Gjermo P., Rølla G., Johansen J. R. Comparison of the effect of chlorhexidine and CuSO4 on plaque formation and development of gingivitis. J Clin Periodontol. 1984 Mar;11(3):176–180. doi: 10.1111/j.1600-051x.1984.tb01321.x. [DOI] [PubMed] [Google Scholar]
  12. Wåler S. M., Rölla G. Comparison between plaque inhibiting effect of chlorhexidine and aqueous solutions of copper- and silver-ions. Scand J Dent Res. 1982 Apr;90(2):131–133. doi: 10.1111/j.1600-0722.1982.tb01535.x. [DOI] [PubMed] [Google Scholar]
  13. ZAK B. Simple procedure for the single sample determination of serum copper and iron. Clin Chim Acta. 1958 Jul;3(4):328–334. doi: 10.1016/0009-8981(58)90021-4. [DOI] [PubMed] [Google Scholar]

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