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. 1986 Feb;29(2):353–354. doi: 10.1128/aac.29.2.353

In vitro inactivation of aminoglycosides by apalcillin.

D N Wright, D C Hale, B Saxon, J M Matsen
PMCID: PMC176410  PMID: 3717936

Abstract

Apalcillin, at concentrations of 75, 150, 300, and 600 micrograms/ml, was combined in vitro with amikacin, gentamicin, netilmicin, or tobramycin. Incubation at 37 degrees C resulted in an apalcillin concentration-dependent and time-dependent decrease of aminoglycoside activity of up to 60%. Amikacin was the most stable and tobramycin was the least stable aminoglycoside under the conditions tested.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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