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. 1986 Oct;30(4):626–627. doi: 10.1128/aac.30.4.626

Effect of medium, pH, and inoculum size on activity of ceftizoxime and Sch-34343 against anaerobic bacteria.

M V Borobio, A Pascual, M C Dominguez, E J Perea
PMCID: PMC176497  PMID: 3466569

Abstract

The effect of two media, three pH values, and three inoculum densities on the activity of ceftizoxime and Sch-34343 against anaerobic bacteria was evaluated. The activities of both antimicrobial agents were affected by medium composition, especially against Bacteroides fragilis. Changes in pH and inoculum size affected only the activity of ceftizoxime against anaerobic bacteria.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aldridge K. E., Sanders C. V., Janney A., Faro S., Marier R. L. Comparison of the activities of penicillin G and new beta-lactam antibiotics against clinical isolates of Bacteroides species. Antimicrob Agents Chemother. 1984 Sep;26(3):410–413. doi: 10.1128/aac.26.3.410. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Borobio M. V., Nogales M. C., Pascual A., Perea E. J. N-formimidoyl-thienamycin activity against anaerobes: effect of the inoculum, pH and culture media. J Antimicrob Chemother. 1981 Sep;8(3):213–218. doi: 10.1093/jac/8.3.213. [DOI] [PubMed] [Google Scholar]
  3. Chow A. W., Finegold S. M. In-vitro activity of ceftizoxime against anaerobic bacteria and comparison with other cephalosporins. J Antimicrob Chemother. 1982 Nov;10 (Suppl 100):45–50. doi: 10.1093/jac/10.suppl_c.45. [DOI] [PubMed] [Google Scholar]
  4. Drulak M. W., Chow A. W. Comparative in vitro activity of ceftizoxime, cefoperazone, and cefoxitin against anaerobic bacteria. Antimicrob Agents Chemother. 1981 Nov;20(5):683–685. doi: 10.1128/aac.20.5.683. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Eley A., Greenwood D. In vitro activity of ceftizoxime against Bacteroides fragilis: comparison with benzylpenicillin, cephalothin, and cefoxitin. Antimicrob Agents Chemother. 1981 Sep;20(3):332–335. doi: 10.1128/aac.20.3.332. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Fu K. P., Neu H. C. Antibacterial activity of ceftizoxime, a beta-lactamase-stable cephalosporin. Antimicrob Agents Chemother. 1980 Apr;17(4):583–590. doi: 10.1128/aac.17.4.583. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Glupczynski Y., Gordts B., van der Linden M. P., Labbé M., Yourassowsky E., Butzler J. P. Susceptibility of anaerobic bacteria to Sch 34343 and other antibiotics. J Antimicrob Chemother. 1985 Jun;15 (Suppl 100):193–198. doi: 10.1093/jac/15.suppl_c.193. [DOI] [PubMed] [Google Scholar]
  8. Greenwood D., Pearson N., Eley A., O'Grady F. Comparative in vitro activities of cefotaxime and ceftizoxime (FK749): new cephalosporins with exceptional potency. Antimicrob Agents Chemother. 1980 Mar;17(3):397–401. doi: 10.1128/aac.17.3.397. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Jacobus N. V., Tally F. P., Gorbach S. L. Susceptibility of anaerobic bacteria to Sch 34343 and other beta-lactam antibiotics. J Antimicrob Chemother. 1985 Jun;15 (Suppl 100):189–191. doi: 10.1093/jac/15.suppl_c.189. [DOI] [PubMed] [Google Scholar]
  10. Kamimura T., Matsumoto Y., Okada N., Mine Y., Nishida M., Goto S., Kuwahara S. Ceftizoxime (FK 749), a new parenteral cephalosporin: in vitro and in vivo antibacterial activities. Antimicrob Agents Chemother. 1979 Nov;16(5):540–548. doi: 10.1128/aac.16.5.540. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Nord C. E., Olsson-Liljequist B. Comparative in-vitro activity of Sch 34343 and other antimicrobial agents against anaerobic bacteria. J Antimicrob Chemother. 1985 Jun;15 (Suppl 100):183–188. doi: 10.1093/jac/15.suppl_c.183. [DOI] [PubMed] [Google Scholar]
  12. O'Callaghan C. H., Morris A., Kirby S. M., Shingler A. H. Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate. Antimicrob Agents Chemother. 1972 Apr;1(4):283–288. doi: 10.1128/aac.1.4.283. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Rolfe R. D., Finegold S. M. Comparative in vitro activity of new beta-lactam antibiotics against anaerobic bacteria. Antimicrob Agents Chemother. 1981 Nov;20(5):600–609. doi: 10.1128/aac.20.5.600. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Wexler H., Carter W. T., Finegold S. M. In-vitro activity of Sch 34343 against anaerobic bacteria. J Antimicrob Chemother. 1985 Jun;15 (Suppl 100):173–176. doi: 10.1093/jac/15.suppl_c.173. [DOI] [PubMed] [Google Scholar]
  15. Wilkins T. D., Chalgren S. Medium for use in antibiotic susceptibility testing of anaerobic bacteria. Antimicrob Agents Chemother. 1976 Dec;10(6):926–928. doi: 10.1128/aac.10.6.926. [DOI] [PMC free article] [PubMed] [Google Scholar]

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