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. 1986 Nov;30(5):810–812. doi: 10.1128/aac.30.5.810

Tetracycline resistance and tetM in pathogenic urogenital bacteria.

M C Roberts, S L Hillier, J Hale, K K Holmes, G E Kenny
PMCID: PMC176543  PMID: 3800360

Abstract

Clinical isolates of Gardnerella vaginalis, Streptococcus agalactiae, Bacteroides spp., and Mobiluncus spp. were screened for resistance to tetracycline and for the presence of the streptococcal tetM determinant. The S. agalactiae and G. vaginalis strains contained DNA sequences homologous to the tetM determinant, while strains of the other two genera did not.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burdett V. Identification of tetracycline-resistant R-plasmids in Streptococcus agalactiae (group B). Antimicrob Agents Chemother. 1980 Nov;18(5):753–760. doi: 10.1128/aac.18.5.753. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Burdett V., Inamine J., Rajagopalan S. Heterogeneity of tetracycline resistance determinants in Streptococcus. J Bacteriol. 1982 Mar;149(3):995–1004. doi: 10.1128/jb.149.3.995-1004.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Burdett V. Streptococcal tetracycline resistance mediated at the level of protein synthesis. J Bacteriol. 1986 Feb;165(2):564–569. doi: 10.1128/jb.165.2.564-569.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Chang A. C., Cohen S. N. Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. J Bacteriol. 1978 Jun;134(3):1141–1156. doi: 10.1128/jb.134.3.1141-1156.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Franke A. E., Clewell D. B. Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of "conjugal" transfer in the absence of a conjugative plasmid. J Bacteriol. 1981 Jan;145(1):494–502. doi: 10.1128/jb.145.1.494-502.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Gawron-Burke C., Clewell D. B. A transposon in Streptococcus faecalis with fertility properties. Nature. 1982 Nov 18;300(5889):281–284. doi: 10.1038/300281a0. [DOI] [PubMed] [Google Scholar]
  7. Hartley D. L., Jones K. R., Tobian J. A., LeBlanc D. J., Macrina F. L. Disseminated tetracycline resistance in oral streptococci: implication of a conjugative transposon. Infect Immun. 1984 Jul;45(1):13–17. doi: 10.1128/iai.45.1.13-17.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Koutsky L. A., Stamm W. E., Brunham R. C., Stevens C. E., Cole B., Hale J., Davick P., Holmes K. K. Persistence of Mycoplasma hominis after therapy: importance of tetracycline resistance and of coexisting vaginal flora. Sex Transm Dis. 1983 Oct-Dec;10(4 Suppl):374–381. [PubMed] [Google Scholar]
  9. McCarthy L. R., Mickelsen P. A., Smith E. G. Antibiotic susceptibility of Haemophilus vaginalis (Corynebacterium vaginale) to 21 antibiotics. Antimicrob Agents Chemother. 1979 Aug;16(2):186–189. doi: 10.1128/aac.16.2.186. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. McMurry L. M., Cullinane J. C., Petrucci R. E., Jr, Levy S. B. Active uptake of tetracycline by membrane vesicles from susceptible Escherichia coli. Antimicrob Agents Chemother. 1981 Sep;20(3):307–313. doi: 10.1128/aac.20.3.307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Mendez B., Tachibana C., Levy S. B. Heterogeneity of tetracycline resistance determinants. Plasmid. 1980 Mar;3(2):99–108. doi: 10.1016/0147-619x(80)90101-8. [DOI] [PubMed] [Google Scholar]
  12. Morse S. A., Johnson S. R., Biddle J. W., Roberts M. C. High-level tetracycline resistance in Neisseria gonorrhoeae is result of acquisition of streptococcal tetM determinant. Antimicrob Agents Chemother. 1986 Nov;30(5):664–670. doi: 10.1128/aac.30.5.664. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Roberts M. C., Hillier S. L., Schoenknecht F. D., Holmes K. K. Comparison of gram stain, DNA probe, and culture for the identification of species of Mobiluncus in female genital specimens. J Infect Dis. 1985 Jul;152(1):74–77. doi: 10.1093/infdis/152.1.74. [DOI] [PubMed] [Google Scholar]
  14. Roberts M. C., Hillier S. L., Schoenknecht F. D., Holmes K. K. Nitrocellulose filter blots for species identification of Mobiluncus curtisii and Mobiluncus mulieris. J Clin Microbiol. 1984 Oct;20(4):826–827. doi: 10.1128/jcm.20.4.826-827.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Roberts M. C., Kenny G. E. Dissemination of the tetM tetracycline resistance determinant to Ureaplasma urealyticum. Antimicrob Agents Chemother. 1986 Feb;29(2):350–352. doi: 10.1128/aac.29.2.350. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Roberts M. C., Koutsky L. A., Holmes K. K., LeBlanc D. J., Kenny G. E. Tetracycline-resistant Mycoplasma hominis strains contain streptococcal tetM sequences. Antimicrob Agents Chemother. 1985 Jul;28(1):141–143. doi: 10.1128/aac.28.1.141. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Southern E. M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975 Nov 5;98(3):503–517. doi: 10.1016/s0022-2836(75)80083-0. [DOI] [PubMed] [Google Scholar]
  18. Taylor D. E. Plasmid-mediated tetracycline resistance in Campylobacter jejuni: expression in Escherichia coli and identification of homology with streptococcal class M determinant. J Bacteriol. 1986 Mar;165(3):1037–1039. doi: 10.1128/jb.165.3.1037-1039.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]

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