Skip to main content
PMC home page
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 2005 Dec;76(Suppl 5):v2–v7. doi: 10.1136/jnnp.2005.082867

Epidemiology and risk factors of dementia

W M van der Flier, P Scheltens
PMCID: PMC1765715  PMID: 16291918

Full Text

The Full Text of this article is available as a PDF (210.0 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Berr C., Wancata J., Ritchie K. Prevalence of dementia in the elderly in Europe. Eur Neuropsychopharmacol. 2005 Aug;15(4):463–471. doi: 10.1016/j.euroneuro.2005.04.003. [DOI] [PubMed] [Google Scholar]
  2. Breteler M. M. Vascular risk factors for Alzheimer's disease: an epidemiologic perspective. Neurobiol Aging. 2000 Mar-Apr;21(2):153–160. doi: 10.1016/s0197-4580(99)00110-4. [DOI] [PubMed] [Google Scholar]
  3. Fratiglioni L., Launer L. J., Andersen K., Breteler M. M., Copeland J. R., Dartigues J. F., Lobo A., Martinez-Lage J., Soininen H., Hofman A. Incidence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology. 2000;54(11 Suppl 5):S10–S15. [PubMed] [Google Scholar]
  4. Harvey R. J., Skelton-Robinson M., Rossor M. N. The prevalence and causes of dementia in people under the age of 65 years. J Neurol Neurosurg Psychiatry. 2003 Sep;74(9):1206–1209. doi: 10.1136/jnnp.74.9.1206. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Kivipelto Miia, Helkala Eeva-Liisa, Laakso Mikko P., Hänninen Tuomo, Hallikainen Merja, Alhainen Kari, Iivonen Susan, Mannermaa Arto, Tuomilehto Jaakko, Nissinen Aulikki. Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med. 2002 Aug 6;137(3):149–155. doi: 10.7326/0003-4819-137-3-200208060-00006. [DOI] [PubMed] [Google Scholar]
  6. Korf Esther S. C., White Lon R., Scheltens Philip, Launer Lenore J. Midlife blood pressure and the risk of hippocampal atrophy: the Honolulu Asia Aging Study. Hypertension. 2004 May 24;44(1):29–34. doi: 10.1161/01.HYP.0000132475.32317.bb. [DOI] [PubMed] [Google Scholar]
  7. Lander E. S. The new genomics: global views of biology. Science. 1996 Oct 25;274(5287):536–539. doi: 10.1126/science.274.5287.536. [DOI] [PubMed] [Google Scholar]
  8. Launer L. J., Brock D. B. Population-based studies of AD: message and methods: an epidemiologic view. Stat Med. 2004 Jan 30;23(2):191–197. doi: 10.1002/sim.1708. [DOI] [PubMed] [Google Scholar]
  9. Launer L. J., Ross G. W., Petrovitch H., Masaki K., Foley D., White L. R., Havlik R. J. Midlife blood pressure and dementia: the Honolulu-Asia aging study. Neurobiol Aging. 2000 Jan-Feb;21(1):49–55. doi: 10.1016/s0197-4580(00)00096-8. [DOI] [PubMed] [Google Scholar]
  10. Launer L. J. The epidemiologic study of dementia: a life-long quest? Neurobiol Aging. 2005 Mar;26(3):335–340. doi: 10.1016/j.neurobiolaging.2004.03.016. [DOI] [PubMed] [Google Scholar]
  11. Launer Lenore J. Demonstrating the case that AD is a vascular disease: epidemiologic evidence. Ageing Res Rev. 2002 Feb;1(1):61–77. doi: 10.1016/s0047-6374(01)00364-5. [DOI] [PubMed] [Google Scholar]
  12. Lobo A., Launer L. J., Fratiglioni L., Andersen K., Di Carlo A., Breteler M. M., Copeland J. R., Dartigues J. F., Jagger C., Martinez-Lage J. Prevalence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology. 2000;54(11 Suppl 5):S4–S9. [PubMed] [Google Scholar]
  13. Matthews Fiona, Brayne Carol, Medical Research Council Cognitive Function and Ageing Study Investigators The incidence of dementia in England and Wales: findings from the five identical sites of the MRC CFA Study. PLoS Med. 2005 Aug 23;2(8):e193–e193. doi: 10.1371/journal.pmed.0020193. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E. M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984 Jul;34(7):939–944. doi: 10.1212/wnl.34.7.939. [DOI] [PubMed] [Google Scholar]
  15. Miech R. A., Breitner J. C. S., Zandi P. P., Khachaturian A. S., Anthony J. C., Mayer L. Incidence of AD may decline in the early 90s for men, later for women: The Cache County study. Neurology. 2002 Jan 22;58(2):209–218. doi: 10.1212/wnl.58.2.209. [DOI] [PubMed] [Google Scholar]
  16. Petersen R. C., Smith G. E., Waring S. C., Ivnik R. J., Tangalos E. G., Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999 Mar;56(3):303–308. doi: 10.1001/archneur.56.3.303. [DOI] [PubMed] [Google Scholar]
  17. Qiu Chengxuan, Winblad Bengt, Fratiglioni Laura. The age-dependent relation of blood pressure to cognitive function and dementia. Lancet Neurol. 2005 Aug;4(8):487–499. doi: 10.1016/S1474-4422(05)70141-1. [DOI] [PubMed] [Google Scholar]
  18. Strittmatter W. J., Roses A. D. Apolipoprotein E and Alzheimer disease. Proc Natl Acad Sci U S A. 1995 May 23;92(11):4725–4727. doi: 10.1073/pnas.92.11.4725. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Wancata Johannes, Musalek M., Alexandrowicz R., Krautgartner M. Number of dementia sufferers in Europe between the years 2000 and 2050. Eur Psychiatry. 2003 Oct;18(6):306–313. doi: 10.1016/j.eurpsy.2003.03.003. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES