Full Text
The Full Text of this article is available as a PDF (71.6 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Anderson D. M., Kumaki S., Ahdieh M., Bertles J., Tometsko M., Loomis A., Giri J., Copeland N. G., Gilbert D. J., Jenkins N. A. Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes. J Biol Chem. 1995 Dec 15;270(50):29862–29869. doi: 10.1074/jbc.270.50.29862. [DOI] [PubMed] [Google Scholar]
- Bathon J. M., Martin R. W., Fleischmann R. M., Tesser J. R., Schiff M. H., Keystone E. C., Genovese M. C., Wasko M. C., Moreland L. W., Weaver A. L. A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis. N Engl J Med. 2000 Nov 30;343(22):1586–1593. doi: 10.1056/NEJM200011303432201. [DOI] [PubMed] [Google Scholar]
- Bondeson J., Foxwell B., Brennan F., Feldmann M. Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5668–5673. doi: 10.1073/pnas.96.10.5668. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dinarello C. A. IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family. J Allergy Clin Immunol. 1999 Jan;103(1 Pt 1):11–24. doi: 10.1016/s0091-6749(99)70518-x. [DOI] [PubMed] [Google Scholar]
- Dubois S., Magrangeas F., Lehours P., Raher S., Bernard J., Boisteau O., Leroy S., Minvielle S., Godard A., Jacques Y. Natural splicing of exon 2 of human interleukin-15 receptor alpha-chain mRNA results in a shortened form with a distinct pattern of expression. J Biol Chem. 1999 Sep 17;274(38):26978–26984. doi: 10.1074/jbc.274.38.26978. [DOI] [PubMed] [Google Scholar]
- Ghayur T., Banerjee S., Hugunin M., Butler D., Herzog L., Carter A., Quintal L., Sekut L., Talanian R., Paskind M. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature. 1997 Apr 10;386(6625):619–623. doi: 10.1038/386619a0. [DOI] [PubMed] [Google Scholar]
- Gracie J. A., Forsey R. J., Chan W. L., Gilmour A., Leung B. P., Greer M. R., Kennedy K., Carter R., Wei X. Q., Xu D. A proinflammatory role for IL-18 in rheumatoid arthritis. J Clin Invest. 1999 Nov;104(10):1393–1401. doi: 10.1172/JCI7317. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Joosten L. A., van De Loo F. A., Lubberts E., Helsen M. M., Netea M. G., van Der Meer J. W., Dinarello C. A., van Den Berg W. B. An IFN-gamma-independent proinflammatory role of IL-18 in murine streptococcal cell wall arthritis. J Immunol. 2000 Dec 1;165(11):6553–6558. doi: 10.4049/jimmunol.165.11.6553. [DOI] [PubMed] [Google Scholar]
- Kanakaraj P., Ngo K., Wu Y., Angulo A., Ghazal P., Harris C. A., Siekierka J. J., Peterson P. A., Fung-Leung W. P. Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice. J Exp Med. 1999 Apr 5;189(7):1129–1138. doi: 10.1084/jem.189.7.1129. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Leung B. P., Culshaw S., Gracie J. A., Hunter D., Canetti C. A., Campbell C., Cunha F., Liew F. Y., McInnes I. B. A role for IL-18 in neutrophil activation. J Immunol. 2001 Sep 1;167(5):2879–2886. doi: 10.4049/jimmunol.167.5.2879. [DOI] [PubMed] [Google Scholar]
- Leung B. P., McInnes I. B., Esfandiari E., Wei X. Q., Liew F. Y. Combined effects of IL-12 and IL-18 on the induction of collagen-induced arthritis. J Immunol. 2000 Jun 15;164(12):6495–6502. doi: 10.4049/jimmunol.164.12.6495. [DOI] [PubMed] [Google Scholar]
- Lipsky P. E., van der Heijde D. M., St Clair E. W., Furst D. E., Breedveld F. C., Kalden J. R., Smolen J. S., Weisman M., Emery P., Feldmann M. Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. N Engl J Med. 2000 Nov 30;343(22):1594–1602. doi: 10.1056/NEJM200011303432202. [DOI] [PubMed] [Google Scholar]
- McInnes I. B., Gracie J. A., Leung B. P., Wei X. Q., Liew F. Y. Interleukin 18: a pleiotropic participant in chronic inflammation. Immunol Today. 2000 Jul;21(7):312–315. doi: 10.1016/s0167-5699(00)01648-0. [DOI] [PubMed] [Google Scholar]
- Nakamura S., Otani T., Okura R., Ijiri Y., Motoda R., Kurimoto M., Orita K. Expression and responsiveness of human interleukin-18 receptor (IL-18R) on hematopoietic cell lines. Leukemia. 2000 Jun;14(6):1052–1059. doi: 10.1038/sj.leu.2401789. [DOI] [PubMed] [Google Scholar]
- Parnet P., Garka K. E., Bonnert T. P., Dower S. K., Sims J. E. IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP. J Biol Chem. 1996 Feb 23;271(8):3967–3970. doi: 10.1074/jbc.271.8.3967. [DOI] [PubMed] [Google Scholar]
- Ruchatz H., Leung B. P., Wei X. Q., McInnes I. B., Liew F. Y. Soluble IL-15 receptor alpha-chain administration prevents murine collagen-induced arthritis: a role for IL-15 in development of antigen-induced immunopathology. J Immunol. 1998 Jun 1;160(11):5654–5660. [PubMed] [Google Scholar]
- Spencer-Green G. Etanercept (Enbrel): update on therapeutic use. Ann Rheum Dis. 2000 Nov;59 (Suppl 1):i46–i49. doi: 10.1136/ard.59.suppl_1.i46. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wei X. Q., Leung B. P., Arthur H. M., McInnes I. B., Liew F. Y. Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18. J Immunol. 2001 Jan 1;166(1):517–521. doi: 10.4049/jimmunol.166.1.517. [DOI] [PubMed] [Google Scholar]