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. 2000 Dec;47(Suppl 4):iv63–iv65. doi: 10.1136/gut.47.suppl_4.iv63

Neuroimmune alterations of ENS functioning

L Bueno
PMCID: PMC1766800  PMID: 11076920

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Figure 1  .

Figure 1  

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Interaction between the central nervous system and the immune system. VIP, vasoactive intestinal peptide; SP, substance P; SOM, somatostatin; G, ganglion; GALT, gut associated lymphoid tissue; MLN, mesenteric lymph node. (From Ottaway.20)

Figure 2  .

Figure 2  

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Influence of inflammatory mediators on extrinsic afferent and efferent nerves. LT, leukotriene; PGs, prostaglandins; NGF, nerve growth factor; CGRP, calcitonin gene related peptide; 5-HT, 5-hydroxytryptamine; diHETE, dihydroxyeicosatetraenoic acid.

Figure 3  .

Figure 3  

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Inflammation induced phenotypic changes and mediator release in the gut intrinsic nervous system. IL, interleukin; TNF-α, tumour necrosis factor α; TGF-β, transforming growth factor β; LIF, leukaemia inhibitory factor; ACh, acetylcholine; iNOS, inducible nitric acid synthase; NAd, noradrenaline.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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