Skip to main content
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 2005 Feb;64(Suppl 1):i11–i21. doi: 10.1136/ard.2004.031815

The EULAR–OMERACT rheumatoid arthritis MRI reference image atlas: the metacarpophalangeal joints

P Conaghan, P Bird, B Ejbjerg, P O'Connor, C Peterfy, F McQueen, M Lassere, P Emery, R Shnier, J Edmonds, M Ostergaard
PMCID: PMC1766829  PMID: 15647417

Full Text

The Full Text of this article is available as a PDF (950.3 KB).

Figure 1.

Figure 1

Figure 1

Figure 1

 Synovitis reference image sheets (pages i12–i13, total 2). Reference images for MCP joint synovitis grades 0–3 are presented on two opposing pages. Examples are provided from the low end and high end of each grade. Synovitis is graded 0–3 (normal, mild, moderate, severe) as estimated by thirds of the presumed maximum volume of enhancing tissue as described in the OMERACT RAMRIS (see table 1, reference 17). The MRI set to be assessed should be compared with the axial precontrast and postcontrast T1 weighted reference images and the joint assigned the score of the best possible match. The first MCP joint should not be scored. All axial slices covering the joint should be taken into account. Each of the second to fifth MCP joint should be scored separately. A total score (range 0–12) can be calculated. The diagram above describes the positions and types of images included.

Figure 2.

Figure 2

Figure 2

Figure 2

 Bone oedema reference image sheets (pages i14–i15, total 2). Bone oedema in the metacarpal head and phalangeal base is illustrated on one single-page sheet each. All grades (0–3) are presented. Bone oedema grading is by percentage volume (0–3, by 33% volume increments) of the assessed bone as described in the OMERACT RAMRIS (see table 1, reference 11). The "assessed bone volume" is from the articular surface (or its best estimated position if absent) to a depth of 1 cm. All coronal slices covering the bone need to be assessed to estimate the percentage of the total volume occupied by the oedema. If erosion and oedema are concurrently present, oedema is scored as the proportion of the original bone. The T2 weighted fat saturated reference images of this atlas can be used for guidance and calibration. Each bone of the second to fifth MCP joint should be scored separately. A total score (range 0–24) can be calculated. The diagram above describes the types and positions of images presented.

Figure 3.

Figure 3

Figure 3

Figure 3

Figure 3

Figure 3

 Bone erosion reference image sheets (pages i16–i19, total 4). Bone erosion in the metacarpal head and phalangeal base is illustrated on two single-page sheets each. Grades 0–3 supplemented with examples of three higher grades are presented. Bone erosion grading is by percentage volume (0–10, by 10% volume increments) of the assessed bone volume as described in the OMERACT RAMRIS (see table 1, reference 11). The "assessed bone volume" is defined as described above. The atlas reference images can be used for guidance and calibration. All coronal slices covering the bone should be assessed to estimate the percentage of the total volume occupied by the erosion. The varying number of coronal slices needed to cover the bone reflects varying bone sizes and varying slice thickness (1.5–3 mm). A total score (range 0–80) can be calculated. The diagram above describes the types and positions of images presented.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bird P., Conaghan P., Ejbjerg B., McQueen F., Lassere M., Peterfy C., Edmonds J., Shnier R., O'Connor P., Haavardsholm E. The development of the EULAR-OMERACT rheumatoid arthritis MRI reference image atlas. Ann Rheum Dis. 2005 Feb;64 (Suppl 1):i8–10. doi: 10.1136/ard.2004.031807. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Conaghan Philip, Lassere Marissa, Østergaard Mikkel, Peterfy Charles, McQueen Fiona, O'Connor Philip, Bird Paul, Ejbjerg Bo, Klarlund Mette, Shnier Ron. OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies. Exercise 4: an international multicenter longitudinal study using the RA-MRI Score. J Rheumatol. 2003 Jun;30(6):1376–1379. [PubMed] [Google Scholar]
  3. Felson D. T., Anderson J. J., Boers M., Bombardier C., Chernoff M., Fried B., Furst D., Goldsmith C., Kieszak S., Lightfoot R. The American College of Rheumatology preliminary core set of disease activity measures for rheumatoid arthritis clinical trials. The Committee on Outcome Measures in Rheumatoid Arthritis Clinical Trials. Arthritis Rheum. 1993 Jun;36(6):729–740. doi: 10.1002/art.1780360601. [DOI] [PubMed] [Google Scholar]
  4. Fleming A., Benn R. T., Corbett M., Wood P. H. Early rheumatoid disease. II. Patterns of joint involvement. Ann Rheum Dis. 1976 Aug;35(4):361–364. doi: 10.1136/ard.35.4.361. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Lassere Marissa, McQueen Fiona, Østergaard Mikkel, Conaghan Philip, Shnier Ron, Peterfy Charles, Klarlund Mette, Bird Paul, O'Connor Philip, Stewart Neal. OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies. Exercise 3: an international multicenter reliability study using the RA-MRI Score. J Rheumatol. 2003 Jun;30(6):1366–1375. [PubMed] [Google Scholar]
  6. Ostendorf B., Peters R., Dann P., Becker A., Scherer A., Wedekind F., Friemann J., Schulitz K. P., Mödder U., Schneider M. Magnetic resonance imaging and miniarthroscopy of metacarpophalangeal joints: sensitive detection of morphologic changes in rheumatoid arthritis. Arthritis Rheum. 2001 Nov;44(11):2492–2502. doi: 10.1002/1529-0131(200111)44:11<2492::aid-art429>3.0.co;2-x. [DOI] [PubMed] [Google Scholar]
  7. Ostergaard M., Klarlund M., Lassere M., Conaghan P., Peterfy C., McQueen F., O'Connor P., Shnier R., Stewart N., McGonagle D. Interreader agreement in the assessment of magnetic resonance images of rheumatoid arthritis wrist and finger joints--an international multicenter study. J Rheumatol. 2001 May;28(5):1143–1150. [PubMed] [Google Scholar]
  8. Tuokko J., Nejentsev S., Luukkainen R., Toivanen A., Ilonen J. HLA haplotype analysis in Finnish patients with rheumatoid arthritis. Arthritis Rheum. 2001 Feb;44(2):315–322. doi: 10.1002/1529-0131(200102)44:2<315::AID-ANR48>3.0.CO;2-G. [DOI] [PubMed] [Google Scholar]
  9. van der Heijde D. M. Plain X-rays in rheumatoid arthritis: overview of scoring methods, their reliability and applicability. Baillieres Clin Rheumatol. 1996 Aug;10(3):435–453. doi: 10.1016/s0950-3579(96)80043-4. [DOI] [PubMed] [Google Scholar]
  10. Østergaard M., Edmonds J., McQueen F., Peterfy C., Lassere M., Ejbjerg B., Bird P., Emery P., Genant H., Conaghan P. An introduction to the EULAR-OMERACT rheumatoid arthritis MRI reference image atlas. Ann Rheum Dis. 2005 Feb;64 (Suppl 1):i3–i7. doi: 10.1136/ard.2004.031773. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES