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. 2005 Mar;64(Suppl 2):ii46–ii48. doi: 10.1136/ard.2004.030817

Ethical and practical issues in conducting clinical trials in psoriasis and psoriatic arthritis

A Kavanaugh
PMCID: PMC1766869  PMID: 15708936

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bodenheimer T. Uneasy alliance--clinical investigators and the pharmaceutical industry. N Engl J Med. 2000 May 18;342(20):1539–1544. doi: 10.1056/NEJM200005183422024. [DOI] [PubMed] [Google Scholar]
  2. Djulbegovic B., Lacevic M., Cantor A., Fields K. K., Bennett C. L., Adams J. R., Kuderer N. M., Lyman G. H. The uncertainty principle and industry-sponsored research. Lancet. 2000 Aug 19;356(9230):635–638. doi: 10.1016/S0140-6736(00)02605-2. [DOI] [PubMed] [Google Scholar]
  3. Forster H. P., Emanuel E., Grady C. The 2000 revision of the Declaration of Helsinki: a step forward or more confusion? Lancet. 2001 Oct 27;358(9291):1449–1453. doi: 10.1016/S0140-6736(01)06534-5. [DOI] [PubMed] [Google Scholar]
  4. HILL A. B. Medical ethics and controlled trials. Br Med J. 1963 Apr 20;1(5337):1043–1049. doi: 10.1136/bmj.1.5337.1043. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Kahn J. P., Mastroianni A. C. Moving from compliance to conscience: why we can and should improve on the ethics of clinical research. Arch Intern Med. 2001 Apr 9;161(7):925–928. doi: 10.1001/archinte.161.7.925. [DOI] [PubMed] [Google Scholar]
  6. Kleijnen J., de Craen A. J., van Everdingen J., Krol L. Placebo effect in double-blind clinical trials: a review of interactions with medications. Lancet. 1994 Nov 12;344(8933):1347–1349. doi: 10.1016/s0140-6736(94)90699-8. [DOI] [PubMed] [Google Scholar]
  7. Lewis John A., Jonsson Bertil, Kreutz Gottfried, Sampaio Cristina, van Zwieten-Boot Barbara. Placebo-controlled trials and the Declaration of Helsinki. Lancet. 2002 Apr 13;359(9314):1337–1340. doi: 10.1016/S0140-6736(02)08277-6. [DOI] [PubMed] [Google Scholar]
  8. Montaner J. S., O'Shaughnessy M. V., Schechter M. T. Industry-sponsored clinical research: a double-edged sword. Lancet. 2001 Dec 1;358(9296):1893–1895. doi: 10.1016/S0140-6736(01)06891-X. [DOI] [PubMed] [Google Scholar]
  9. Montori V. M., Smieja M., Guyatt G. H. Publication bias: a brief review for clinicians. Mayo Clin Proc. 2000 Dec;75(12):1284–1288. doi: 10.4065/75.12.1284. [DOI] [PubMed] [Google Scholar]
  10. Rothman K. J., Michels K. B. The continuing unethical use of placebo controls. N Engl J Med. 1994 Aug 11;331(6):394–398. doi: 10.1056/NEJM199408113310611. [DOI] [PubMed] [Google Scholar]
  11. Shapiro H. T., Meslin E. M. Ethical issues in the design and conduct of clinical trials in developing countries. N Engl J Med. 2001 Jul 12;345(2):139–142. doi: 10.1056/NEJM200107123450212. [DOI] [PubMed] [Google Scholar]
  12. Stein C. M., Pincus T. Placebo-controlled studies in rheumatoid arthritis: ethical issues. Lancet. 1999 Jan 30;353(9150):400–403. doi: 10.1016/S0140-6736(98)01373-7. [DOI] [PubMed] [Google Scholar]

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