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. 2001 Dec;49(Suppl 4):iv29–iv35. doi: 10.1136/gut.49.suppl_4.iv29

Pancreatic surgical complications—the case for prophylaxis

C Gouillat, J Gigot
PMCID: PMC1766893  PMID: 11878792

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bartoli F. G., Arnone G. B., Ravera G., Bachi V. Pancreatic fistula and relative mortality in malignant disease after pancreaticoduodenectomy. Review and statistical meta-analysis regarding 15 years of literature. Anticancer Res. 1991 Sep-Oct;11(5):1831–1848. [PubMed] [Google Scholar]
  2. Beguiristain A., Espí A., Balen E., Pardo F., Hernández Lizoaín J. L., Alvarez Cienfuegos J. Profilaxis con Somatostatina tras duodenopancreatectomía cefálica. Rev Esp Enferm Dig. 1995 Mar;87(3):221–224. [PubMed] [Google Scholar]
  3. Berberat P. O., Friess H., Uhl W., Büchler M. W. The role of octreotide in the prevention of complications following pancreatic resection. Digestion. 1999;60 (Suppl 2):15–22. doi: 10.1159/000051476. [DOI] [PubMed] [Google Scholar]
  4. Bradley E. L., 3rd Complications of chronic pancreatitis. Surg Clin North Am. 1989 Jun;69(3):481–497. doi: 10.1016/s0039-6109(16)44832-2. [DOI] [PubMed] [Google Scholar]
  5. Bruns C., Weckbecker G., Raulf F., Kaupmann K., Schoeffter P., Hoyer D., Lübbert H. Molecular pharmacology of somatostatin-receptor subtypes. Ann N Y Acad Sci. 1994 Sep 15;733:138–146. doi: 10.1111/j.1749-6632.1994.tb17263.x. [DOI] [PubMed] [Google Scholar]
  6. Buscail L., Saint-Laurent N., Chastre E., Vaillant J. C., Gespach C., Capella G., Kalthoff H., Lluis F., Vaysse N., Susini C. Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer. Cancer Res. 1996 Apr 15;56(8):1823–1827. [PubMed] [Google Scholar]
  7. Büchler M., Friess H. Inhibition of pancreatic secretion to prevent postoperative complications following pancreatic resection. Acta Gastroenterol Belg. 1993 May-Aug;56(3-4):271–278. [PubMed] [Google Scholar]
  8. Büchler M., Friess H., Klempa I., Hermanek P., Sulkowski U., Becker H., Schafmayer A., Baca I., Lorenz D., Meister R. Role of octreotide in the prevention of postoperative complications following pancreatic resection. Am J Surg. 1992 Jan;163(1):125–131. doi: 10.1016/0002-9610(92)90264-r. [DOI] [PubMed] [Google Scholar]
  9. Büchler M., Friess H. Prevention of postoperative complications following pancreatic surgery. Digestion. 1993;54 (Suppl 1):41–46. doi: 10.1159/000201076. [DOI] [PubMed] [Google Scholar]
  10. DiCarlo V., Balzano G., Zerbi A., Villa E. Pancreatic cancer resection in elderly patients. Br J Surg. 1998 May;85(5):607–610. doi: 10.1046/j.1365-2168.1998.00685.x. [DOI] [PubMed] [Google Scholar]
  11. Forrest J. F., Longmire W. P., Jr Carcinoma of the pancreas and periampullary region. Ann Surg. 1979 Feb;189(2):129–138. doi: 10.1097/00000658-197902000-00001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Friess H., Beger H. G., Sulkowski U., Becker H., Hofbauer B., Dennler H. J., Büchler M. W. Randomized controlled multicentre study of the prevention of complications by octreotide in patients undergoing surgery for chronic pancreatitis. Br J Surg. 1995 Sep;82(9):1270–1273. doi: 10.1002/bjs.1800820938. [DOI] [PubMed] [Google Scholar]
  13. Gullo L., Priori P., Scarpignato C., Baldoni F., Mattioli G., Barbara L. Effect of somatostatin 14 on pure human pancreatic secretion. Dig Dis Sci. 1987 Oct;32(10):1065–1070. doi: 10.1007/BF01300189. [DOI] [PubMed] [Google Scholar]
  14. Hamanaka Y., Nishihara K., Hamasaki T., Kawabata A., Yamamoto S., Tsurumi M., Ueno T., Suzuki T. Pancreatic juice output after pancreatoduodenectomy in relation to pancreatic consistency, duct size, and leakage. Surgery. 1996 Mar;119(3):281–287. doi: 10.1016/s0039-6060(96)80114-0. [DOI] [PubMed] [Google Scholar]
  15. Hamanaka Y., Nishihara K., Hamasaki T., Kawabata A., Yamamoto S., Tsurumi M., Ueno T., Suzuki T. Pancreatic juice output after pancreatoduodenectomy in relation to pancreatic consistency, duct size, and leakage. Surgery. 1996 Mar;119(3):281–287. doi: 10.1016/s0039-6060(96)80114-0. [DOI] [PubMed] [Google Scholar]
  16. Heintges T., Lüthen R., Niederau C. Inhibition of exocrine pancreatic secretion by somatostatin and its analogues. Digestion. 1994;55 (Suppl 1):1–9. [PubMed] [Google Scholar]
  17. Jenkins S. A., Nott D. M., Baxter J. N. Fluctuations in the secretion of pancreatic enzymes between consecutive doses of octreotide: implications for the management of fistulae. Eur J Gastroenterol Hepatol. 1995 Mar;7(3):255–258. [PubMed] [Google Scholar]
  18. Klempa I., Schwedes U., Usadel K. H. Verhütung von postoperativen pankreatitischen Komplikationen nach Duodenopankreatektomie durch Somatostatin. Chirurg. 1979 Jul;50(7):427–431. [PubMed] [Google Scholar]
  19. Kubota A., Yamada Y., Kagimoto S., Shimatsu A., Imamura M., Tsuda K., Imura H., Seino S., Seino Y. Identification of somatostatin receptor subtypes and an implication for the efficacy of somatostatin analogue SMS 201-995 in treatment of human endocrine tumors. J Clin Invest. 1994 Mar;93(3):1321–1325. doi: 10.1172/JCI117090. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Kutz K., Nüesch E., Rosenthaler J. Pharmacokinetics of SMS 201-995 in healthy subjects. Scand J Gastroenterol Suppl. 1986;119:65–72. doi: 10.3109/00365528609087433. [DOI] [PubMed] [Google Scholar]
  21. Lamberts S. W., van der Lely A. J., de Herder W. W., Hofland L. J. Octreotide. N Engl J Med. 1996 Jan 25;334(4):246–254. doi: 10.1056/NEJM199601253340408. [DOI] [PubMed] [Google Scholar]
  22. Lowy A. M., Lee J. E., Pisters P. W., Davidson B. S., Fenoglio C. J., Stanford P., Jinnah R., Evans D. B. Prospective, randomized trial of octreotide to prevent pancreatic fistula after pancreaticoduodenectomy for malignant disease. Ann Surg. 1997 Nov;226(5):632–641. doi: 10.1097/00000658-199711000-00008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Montorsi M., Zago M., Mosca F., Capussotti L., Zotti E., Ribotta G., Fegiz G., Fissi S., Roviaro G., Peracchia A. Efficacy of octreotide in the prevention of pancreatic fistula after elective pancreatic resections: a prospective, controlled, randomized clinical trial. Surgery. 1995 Jan;117(1):26–31. doi: 10.1016/s0039-6060(05)80225-9. [DOI] [PubMed] [Google Scholar]
  24. Patel Y. C., Greenwood M. T., Warszynska A., Panetta R., Srikant C. B. All five cloned human somatostatin receptors (hSSTR1-5) are functionally coupled to adenylyl cyclase. Biochem Biophys Res Commun. 1994 Jan 28;198(2):605–612. doi: 10.1006/bbrc.1994.1088. [DOI] [PubMed] [Google Scholar]
  25. Patel Y. C., Srikant C. B. Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5). Endocrinology. 1994 Dec;135(6):2814–2817. doi: 10.1210/endo.135.6.7988476. [DOI] [PubMed] [Google Scholar]
  26. Pederzoli P., Bassi C., Falconi M., Camboni M. G. Efficacy of octreotide in the prevention of complications of elective pancreatic surgery. Italian Study Group. Br J Surg. 1994 Feb;81(2):265–269. doi: 10.1002/bjs.1800810237. [DOI] [PubMed] [Google Scholar]
  27. Reichlin S. Somatostatin. N Engl J Med. 1983 Dec 15;309(24):1495–1501. doi: 10.1056/NEJM198312153092406. [DOI] [PubMed] [Google Scholar]
  28. Rosenberg L., MacNeil P., Turcotte L. Economic evaluation of the use of octreotide for prevention of complications following pancreatic resection. J Gastrointest Surg. 1999 May-Jun;3(3):225–232. doi: 10.1016/s1091-255x(99)80064-x. [DOI] [PubMed] [Google Scholar]
  29. Sheppard M., Shapiro B., Pimstone B., Kronheim S., Berelowitz M., Gregory M. Metabolic clearance and plasma half-disappearance time of exogenous somatostatin in man. J Clin Endocrinol Metab. 1979 Jan;48(1):50–53. doi: 10.1210/jcem-48-1-50. [DOI] [PubMed] [Google Scholar]
  30. Sohn T. A., Yeo C. J., Cameron J. L., Lillemoe K. D., Talamini M. A., Hruban R. H., Sauter P. K., Coleman J., Ord S. E., Grochow L. B. Should pancreaticoduodenectomy be performed in octogenarians? J Gastrointest Surg. 1998 May-Jun;2(3):207–216. doi: 10.1016/s1091-255x(98)80014-0. [DOI] [PubMed] [Google Scholar]
  31. Trede M., Schwall G. The complications of pancreatectomy. Ann Surg. 1988 Jan;207(1):39–47. doi: 10.1097/00000658-198801000-00009. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Yeo C. J., Cameron J. L., Maher M. M., Sauter P. K., Zahurak M. L., Talamini M. A., Lillemoe K. D., Pitt H. A. A prospective randomized trial of pancreaticogastrostomy versus pancreaticojejunostomy after pancreaticoduodenectomy. Ann Surg. 1995 Oct;222(4):580–592. doi: 10.1097/00000658-199510000-00014. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Yeo C. J. Does prophylactic octreotide benefit patients undergoing elective pancreatic resection? J Gastrointest Surg. 1999 May-Jun;3(3):223–224. doi: 10.1016/s1091-255x(99)80063-8. [DOI] [PubMed] [Google Scholar]

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