Table 2.
Comparison of coagulation factors between patients after total cavopulmonary connection (TCPC) and the control groups
| Children | p Value | Young adults | p Value | |||
| TCPC (n = 78) | Control (n = 37) | TCPC (n = 24) | Control (n = 18) | |||
| Age (years) | 8.8 (2.8) | 9.4 (3.1) | NS | 18.4 (2.5) | 20.1 (5.4) | NS |
| APTT ratio | 1.06 (0.08) | 1.05 (0.12) | NS | 1.02 (0.08) | 1.02 (0.08) | NS |
| INR | 1.13 (0.09) | 1.05 (0.07) | <0.001 | 1.10 (0.09) | 1.03 (0.09) | 0.018 |
| Fibrinogen (g/l) | 2.39 (0.47) | 2.58 (0.34) | 0.029 | 2.15 (0.43) | 2.80 (0.59) | <0.001 |
| Factor V (%) | 83 (18) | 106 (16) | <0.001 | 83 (25) | 108 (19) | 0.001 |
| Factor VII (%) | 69 (18) | 84 (18) | <0.001 | 73 (20) | 91 (15) | 0.003 |
| Antithrombin III (%) | 114 (16) | 102 (11) | <0.001 | 118 (16) | 108 (11) | 0.034 |
| Protein C (%) | 71 (17) | 98 (18) | <0.001 | 83 (20) | 98 (17) | 0.015 |
Data are mean (SD).
APTT, activated partial thromboplastin time; INR, international normalised ratio; NS, not significant.