Table 2.
Outcome | All patients with acute coronary syndromes | ||||
No clopidogrel + no statin (n = 331) | Clopidogrel + no statin (n = 180) | Clopidogrel + CYP3A4 (n = 561) | Clopidogrel + non-CYP3A4 (n = 91) | p Value* | |
Death | 57 (17.2%) | 18 (10%) | 32 (5.7%) | 3 (3.3%) | 0.24 |
MI | 14 (8.3%) | 10 (8.9%) | 28 (7.6%) | 9 (9.7%) | 0.39 |
Stroke | 3 (1.1%) | 2 (1.3%) | 5 (1.4%) | 0 (0%) | 0.70 |
MACE | 73 (22.1%) | 30 (16.7%) | 64 (11.4%) | 12 (13.2%) | 0.54 |
*Comparisons between patients who received CYP3A4 statin versus a non-CYP3A4 statin with clopidogrel.
MACE, major adverse cardiac outcomes (composite of death, MI, and stroke).