Table 2.

 Clinical characteristics and macroscopic necropsy findings in study subjects by age

	Age group (years)
	1 (20–40) (n = 15)	2 (41–60) (n = 17)	3 (⩾61) (n = 16)	p Value*
Men/women	10/5	13/4	9/7
Age (years)	29.1 (1.6)	49.8 (0.90)	71.3 (1.1)
Clinical history
Coronary artery disease	0	2	9	<0.001
Other atherosclerotic disease	0	2	3	<0.001
Hypertension	0	4	6	<0.001
Diabetes	0	1	4	<0.001
Smoking	1	1	4	0.031
Cholesterol >6.0 mmol/l	0	6	4	NS
HDL cholesterol <1 mmol/l	0	3	3	NS
Necropsy findings (macroscopic)
Aortic valve
Normal	15	14	9
Fatty changes	0	3	4
Calcified	0	0	2
Leaky	0	0	1	0.008
Coronary arteries
Normal	5	0	0
Fatty streaks	8	3	3
Small atheromas (<50%)	2	9	4
Significant atheromas (⩾50%)	0	1	1
Complicated lesions	0	4	8	<0.001
Acute myocardial infarction	0	2	2	NS
Number of affected coronary arteries
0	5	0	0
1	0	1	3
⩾2	9	10	12
Diffuse	1	6	1	NS

Data are number of subjects or mean (SEM).

*p Value between the three age groups.

HDL, high density lipoprotein; NS, not significant