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. 1995 Jul;177(14):4144–4148. doi: 10.1128/jb.177.14.4144-4148.1995

Translation of the open reading frame encoded by comS, a gene of the srf operon, is necessary for the development of genetic competence, but not surfactin biosynthesis, in Bacillus subtilis.

C D'Souza 1, M M Nakano 1, D L Frisby 1, P Zuber 1
PMCID: PMC177150  PMID: 7608091

Abstract

A small open reading frame, comS of the srf operon, is the site of mutations that impair competence development in Bacillus subtilis. comS open reading frame translation was required for competence, as was confirmed by the suppression of a comS amber mutation [comS(Am)] by the nonsense suppressor sup-3. comS(Am), when introduced into the srf operon, eliminated late competence gene expression but had no significant effect on surfactin production.

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Selected References

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