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. 1995 Aug;177(15):4528–4531. doi: 10.1128/jb.177.15.4528-4531.1995

Interruption of the ferredoxin (flavodoxin) NADP+ oxidoreductase gene of Escherichia coli does not affect anaerobic growth but increases sensitivity to paraquat.

V Bianchi 1, E Haggård-Ljungquist 1, E Pontis 1, P Reichard 1
PMCID: PMC177208  PMID: 7635836

Abstract

Ferredoxin (flavodoxin) NADP+ oxidoreductase participates in methionine biosynthesis and in the function of two anaerobic enzymes, pyruvate formate-lyase and ribonucleotide reductase. We prepared insertion mutants of Escherichia coli lacking a functional enzyme. They do not require methionine and they grow well anaerobically, but they show increased sensitivity to paraquat.

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Selected References

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