Table 2.

Effect of Helicobacter pylori and other agents on cGMP generation by isolated chief cells

Agent	cGMP (%)
Carbachol (10 μM)	17.13% (0.3)*
H pylori (107 cfu)	9.86% (0.2)*
Carbachol (10 μM)+l-NMMA (mM)	4.28% (0.6)
H pylori (107 cfu)+l-NMMA (mM)	1.48% (0.6)

Results are expressed as per cent of increase over basal values. Basal concentrations of cGMP were 5.37 (0.5) fmol/10⁶ cells (four experiments).

*p<0.05.

Carbachol, carbamylcholine;l-NMMA, N^w-monomethyl-l-arginine.