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. 2002 Mar;50(3):336–340. doi: 10.1136/gut.50.3.336

Table 2.

Frequency of the diverse HLA haplotypes in patients with coeliac disease (CD) and in healthy controls

Typical versus atypical
Healthy controls (n=116) Typical CD (n=79) Atypical CD (n=54) pc OR (95% CI) EF
DR7/DQB1*0201 28 (24.13%) 41 (51.89%)* 13 (24%) 0.02 3.4 (1.58–7.29) 0.40
B8/DR3/DQB1*0201 12 (10.34%) 32 (40,5%)† 40 (74%)‡ 0.001 4.19 (1.97–8.84) 0.56

OR, odds ratio; 95% CI, 95% confidence interval; EF, ethiological fraction.

*pc=0.0026, OR=3.38, 95% CI (1.84–6.11), EF=0.36 (typical CD v healthy controls)

†pc=0.00003, OR=5.78, 95% CI (2.74–12.06), EF=0.33 (typical CD v healthy controls)

‡pc<10-6, OR=24.28, 95% CI (10.27–56.26), EF=0.71 (atypical CD v healthy controls).