Table 3.
Major histocompatibility complex class I chain related gene A (MICA) TM alleles in Spanish coeliac disease (CD) patients and controls
| Atypical versus typical | ||||||
| Allele genotype | Atypical (n=54) | Typical (n=79) | Controls (n=116) | pc | OR (95% CI) | EF |
| 5.1 | 49 (90.74%)* | 42 (53%) | 51 (44%) | 0.00006 | 8.63 (3.11–23.94) | 0.81 |
| 4 | 9 (16.66%) | 19 (24%) | 30 (25.86%) | — | — | — |
| 5 | 7 (13%) | 20 (25%) | 33 (28.44%) | — | — | — |
| 6 | 21 (39%) | 42 (53%) | 50 (43.1%) | — | — | — |
| 9 | 6 (11.11%) | 13 (16%) | 35 (30.17%) | — | — | — |
OR, odds ratio; 95% CI, 95% confidence interval; EF, ethiological fraction.
*pc<10−6, OR=12.5, 95% CI (4.66–33.11), EF=0.84 (atypical v healthy controls).