Figure 8.
Histological appearances of carbon tetrachloride (CCl4) induced rat liver fibrosis with (B, D) and without (A, C) oestradiol administration at 24 weeks (silver impregnation, scale bar = 300 μm). The liver of a male rat administered oestradiol (B) showed less extensive fibrosis and architectural alterations than the liver of a rat without oestradiol administration (A). These alterations were more evident in females (C, D: livers of female rats without and with oestradiol administration, respectively).