Figure 4.

 Immunohistochemical staining for 3-nitrotyrosine in inducible nitric oxide synthase (iNOS) wild-type mice with gastritis (A) and adenoma (B). (A) 3-Nitrotyrosine protein was located primarily in the cytoplasm of inflammatory cells such as macrophages (arrow) and some fibroblasts (arrowhead) in the area of foveolar epithelial hyperplasia (original magnification ×200). (B) 3-Nitrotyrosine protein was located primarily in the cytoplasm of fibroblasts (arrow) in the area of the lamina propria of adenoma lesions (original magnification ×200).