Table 3.

 Other histopathological abnormalities in 115 patients with chronic idiopathic intestinal pseudo-obstruction (CIIP) in comparison with α-actin deficiency

α-Actin deficiency	28 (24%)
Neuropathic
Degenerative neuropathy	20 (17%)
Inflammatory plexitis	20 (17%)
Lymphocytic ganglionitis	13 (11%)
Myopathic
Degenerative leiomyopathy	16 (14%)
Vacuolar myopathy	7 (6%)
Hollow visceral myopathy	4 (3%)
Inclusion body myopathy	4 (3%)
Inflammatory leiomyositis	1 (1%)
Interstitial cell abnormalities
Decreased number ICCs	2 (15%)*

ICCs, interstitial cells of Cajal.

*From n = 13: recent Swedish series only. Less marked alterations were also noted in other patients, including focal decreases in ICC number around ganglia and hyperplasia/hypertrophy.