Figure 1.

 A 56 year old woman with chronic hepatitis C genotype 2c in whom two alanine aminotransferase flares occurred during follow up, and significant worsening of liver fibrosis was revealed by sequential liver biopsies. The patient achieved a sustained virological response following six months of treatment with interferon IFN α2b (3 MU/three times a week) and ribavirin (1 g/day) (IFN+RIBA).