Figure 1.

 Time course effect of intracisternal injection of corticotropin releasing factor (CRF) on hepatic surface perfusion (A) and portal venous pressure (B). After measurement of a 20 minute basal hepatic surface perfusion and portal pressure by laser Doppler flowmetry and pressure transducer, respectively, CRF (2 nmol) or 0.9% saline vehicle was injected intracisternally. Change in hepatic surface perfusion and portal pressure was monitored thereafter for 120 minutes. Each point represents the mean (SEM). *p<0.05, **p <0.01 compared with the basal period.