Abstract
The effects of penicillin and picrotoxin on the increase in membrane conductance produced by γ-aminobutyric acid (GABA) at the hermit crab neuromuscular junction were investigated. Penicillin failed to block the effects of GABA, while picrotoxin proved to be a potent antagonist.
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Selected References
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- Curtis D. R., Game C. J., Johnston G. A., McCulloch R. M., MacLachlan R. M. Convulsive action of penicillin. Brain Res. 1972 Aug 11;43(1):242–245. doi: 10.1016/0006-8993(72)90288-0. [DOI] [PubMed] [Google Scholar]
- DUDEL J., KUFFLER S. W. Presynaptic inhibition at the crayfish neuromuscular junction. J Physiol. 1961 Mar;155:543–562. doi: 10.1113/jphysiol.1961.sp006646. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Earl J., Large W. A. The effects of bicuculline, picrotoxin and strychnine on neuromuscular inhibition in hermit crabs (Eupagurus bernhardus). J Physiol. 1972 Jul;224(1):45P–46P. [PubMed] [Google Scholar]
- Earl J., Large W. A. d-Tubocurarine does not antagonize the inhibitory effects of GABA at the crustacean neuromuscular junction. Brain Res. 1973 Jan 30;49(2):456–458. doi: 10.1016/0006-8993(73)90441-1. [DOI] [PubMed] [Google Scholar]
- Hill R. G., Simmonds M. A., Straughan D. W. Convulsive properties of d-tubocurarine and cortical inhibition. Nature. 1972 Nov 3;240(5375):51–52. doi: 10.1038/240051a0. [DOI] [PubMed] [Google Scholar]
- Obata K., Takeda K., Shinozaki H. Further study on pharmacological properties of the cerebellar-induced inhibition of deiters neurones. Exp Brain Res. 1970 Nov 26;11(4):327–342. doi: 10.1007/BF00237907. [DOI] [PubMed] [Google Scholar]
- Takeuchi A., Onodera K. Effect of bicuculline on the GABA receptor of the crayfish neuromuscular junction. Nat New Biol. 1972 Mar 15;236(63):55–56. doi: 10.1038/newbio236055a0. [DOI] [PubMed] [Google Scholar]
- Takeuchi A., Takeuchi N. A study of the action of picrotoxin on the inhibitory neuromuscular junction of the crayfish. J Physiol. 1969 Nov;205(2):377–391. doi: 10.1113/jphysiol.1969.sp008972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Takeuchi A., Takeuchi N. Anion permeability of the inhibitory post-synaptic membrane of the crayfish neuromuscular junction. J Physiol. 1967 Aug;191(3):575–590. doi: 10.1113/jphysiol.1967.sp008269. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WEIDMANN S. The electrical constants of Purkinje fibres. J Physiol. 1952 Nov;118(3):348–360. doi: 10.1113/jphysiol.1952.sp004799. [DOI] [PMC free article] [PubMed] [Google Scholar]