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. 1973 Feb;47(2):422–424. doi: 10.1111/j.1476-5381.1973.tb08340.x

The ionic composition of aortic smooth muscle from A.S. hypertensive rats

R Massingham, S Shevde
PMCID: PMC1776554  PMID: 4722051

Abstract

The Na+, K+ and Ca2+ content of plasma and aortic vascular smooth muscle from normotensive and A.S.-hypertensive rats have been compared. There was no significant difference in the plasma concentrations of Na+, K+ and Ca2+, or the Na+, K+ and water content or 3H-inulin space of aortic tissue in the two groups.

There was a marked increase in the amount of Ca2+ in the aortae taken from the hypertensive animals as compared with the normotensive animals (P<0·01).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DANIEL E. E., DAWKINS O. Aorta and smooth muscle electrolytes during early and late hypertension. Am J Physiol. 1957 Jul;190(1):70–76. doi: 10.1152/ajplegacy.1957.190.1.71. [DOI] [PubMed] [Google Scholar]
  2. Folkow B., Hallbäck M., Lundgren Y., Weiss L. The effect of intense treatment with hypotensive drugs on structural design of the resistance vessels in spontaneously hypertensive rats. Acta Physiol Scand. 1971 Oct;83(2):280–282. doi: 10.1111/j.1748-1716.1971.tb05078.x. [DOI] [PubMed] [Google Scholar]
  3. HEADINGS V. E., RONDELL P. A., BOHR D. F. Bound soduium in arterv wall. Am J Physiol. 1960 Nov;199:783–787. doi: 10.1152/ajplegacy.1960.199.5.783. [DOI] [PubMed] [Google Scholar]
  4. Hagemeijer F., Rorive G., Schoffeniels E. The ionic composition of rat aortic smooth muscle fibres. Arch Int Physiol Biochim. 1965 Jun;73(3):453–475. doi: 10.3109/13813456509081857. [DOI] [PubMed] [Google Scholar]
  5. Massingham R., Shevde S. Aortic reactivity and electrophysiology in normotensive rats, spontaneously hypertensive rats and rats made hypertensive with desoxycorticosterone plus salt. Br J Pharmacol. 1971 Dec;43(4):868–870. doi: 10.1111/j.1476-5381.1971.tb07224.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Phelan E. L., Wong L. C. Sodium, potassium and water in the tissues of rats with genetic hypertension and constricted renal artery hypertension. Clin Sci. 1968 Dec;35(3):487–494. [PubMed] [Google Scholar]
  7. TOBIAN L., REDLEAF P. D. Ionic composition of the aorta in renal and adrenal hypertension. Am J Physiol. 1958 Feb;192(2):325–330. doi: 10.1152/ajplegacy.1958.192.2.325. [DOI] [PubMed] [Google Scholar]
  8. TOBIAN L. The electrolytes of arterial wall in experimental renal hypertension. Circ Res. 1956 Nov;4(6):671–675. doi: 10.1161/01.res.4.6.671. [DOI] [PubMed] [Google Scholar]
  9. Van Breemen C., McNaughton E. The separation of cell membrane calcium transport from extracellular calcium exchange in vascular smooth muscle. Biochem Biophys Res Commun. 1970 May 22;39(4):567–574. doi: 10.1016/0006-291x(70)90241-x. [DOI] [PubMed] [Google Scholar]

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