Abstract
1 In the perfused superior cervical ganglion of the cat manganese ions (2.7 - 4.6 mM) caused a block of synaptic transmission and reduced the output of acetylcholine.
2 Calcium ions (8.4-10.5 mM) relieved the synaptic block produced by manganese and partially restored the acetylcholine output.
3 The presence of manganese also reduced the sensitivity of ganglion cells to injected acetylcholine.
4 Both effects of manganese were completely reversible.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
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