Abstract
Albuminuria was studied in 40 diabetic children before and after a standardised exercise test, and also in 21 normal children; the results are expressed as geometric mean (95% range) of urine albumin:urine creatinine ratio (mg/mg). There was no significant difference between the mean resting albumin:creatinine ratio in the two groups, or between these ratios before and after exercise in the normal children. In the diabetic children, however, the mean urine albumin:creatinine ratio after exercise was significantly higher than both the value before exercise and the postexercise value of the normal children, with 10 of 40 diabetic children showing a value after exercise greater than the 95% range of the geometric mean of the control group. The diabetic children were also studied by random urine albumin:creatinine ratios and split (erect:supine) 24 hour urine collection; none was abnormal.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Barratt T. M., McLaine P. N., Soothill J. F. Albumin excretion as a measure of glomerular dysfunction in children. Arch Dis Child. 1970 Aug;45(242):496–501. doi: 10.1136/adc.45.242.496. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Davies A. G., Postlethwaite R. J., Price D. A., Burn J. L., Houlton C. A., Fielding B. A. Urinary albumin excretion in school children. Arch Dis Child. 1984 Jul;59(7):625–630. doi: 10.1136/adc.59.7.625. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Deckert T., Poulsen J. E., Larsen M. Prognosis of diabetics with diabetes onset before the age of thirty-one. I. Survival, causes of death, and complications. Diabetologia. 1978 Jun;14(6):363–370. doi: 10.1007/BF01228130. [DOI] [PubMed] [Google Scholar]
- Houser M. Assessment of proteinuria using random urine samples. J Pediatr. 1984 Jun;104(6):845–848. doi: 10.1016/s0022-3476(84)80478-3. [DOI] [PubMed] [Google Scholar]
- Huttunen N. P., Kär M., Puukka R., Akerblom H. K. Exercise-induced proteinuria in children and adolescents with type 1 (insulin dependent) diabetes. Diabetologia. 1981 Nov;21(5):495–497. doi: 10.1007/BF00257792. [DOI] [PubMed] [Google Scholar]
- Koivisto V. A., Huttunen N. P., Vierikko P. Continuous subcutaneous insulin infusion corrects exercise-induced albuminuria in juvenile diabetes. Br Med J (Clin Res Ed) 1981 Mar 7;282(6266):778–779. doi: 10.1136/bmj.282.6266.778-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mogensen C. E., Osterby R., Gundersen H. J. Early functional and morphologic vascular renal consequences of the diabetic state. Diabetologia. 1979 Aug;17(2):71–76. doi: 10.1007/BF01222205. [DOI] [PubMed] [Google Scholar]
- Mogensen C. E., Vittinghus E. Urinary albumin excretion during exercise in juvenile diabetes. A provocation test for early abnormalities. Scand J Clin Lab Invest. 1975 Jul;35(4):295–300. doi: 10.1080/00365517509095743. [DOI] [PubMed] [Google Scholar]
- Viberti G. C., Hill R. D., Jarrett R. J., Argyropoulos A., Mahmud U., Keen H. Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus. Lancet. 1982 Jun 26;1(8287):1430–1432. doi: 10.1016/s0140-6736(82)92450-3. [DOI] [PubMed] [Google Scholar]
- Viberti G. C., Jarrett R. J., McCartney M., Keen H. Increased glomerular permeability to albumin induced by exercise in diabetic subjects. Diabetologia. 1978 May;14(5):293–300. doi: 10.1007/BF01223019. [DOI] [PubMed] [Google Scholar]
- Woo J., Floyd M., Cannon D. C., Kahan B. Radioimmunoassay for urinary albumin. Clin Chem. 1978 Sep;24(9):1464–1467. [PubMed] [Google Scholar]