Abstract
A child presented with raised intracranial pressure for which no cause was established. Five months later a further cerebrospinal fluid examination showed lymphoblasts expressing the common acute lymphoblastic leukaemia phenotype. Bone marrow infiltration was not present. This case illustrates the difficulties that may be encountered in establishing the diagnosis of central nervous system leukaemia.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Greaves M. F., Janossy G., Peto J., Kay H. Immunologically defined subclasses of acute lymphoblastic leukaemia in children: their relationship to presentation features and prognosis. Br J Haematol. 1981 Jun;48(2):179–197. [PubMed] [Google Scholar]
- Hardisty R. M., Norman P. M. Meningeal leukaemia. Arch Dis Child. 1967 Aug;42(224):441–447. doi: 10.1136/adc.42.224.441. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sullivan M. P., Vietti T. J., Fernbach D. J., Griffith K. M., Haddy T. B., Watkins W. L. Clinical investigations in the treatment of meningeal leukemia: radiation therapy regimens vs. conventional intrathecal methotrexate. Blood. 1969 Sep;34(3):301–319. [PubMed] [Google Scholar]